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Main Authors: Yang, Fuming, Li, Yicong, Pfister, Hanspeter, Lichtman, Jeff W., Meirovitch, Yaron
Format: Preprint
Published: 2025
Subjects:
Online Access:https://arxiv.org/abs/2511.00231
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author Yang, Fuming
Li, Yicong
Pfister, Hanspeter
Lichtman, Jeff W.
Meirovitch, Yaron
author_facet Yang, Fuming
Li, Yicong
Pfister, Hanspeter
Lichtman, Jeff W.
Meirovitch, Yaron
contents Petascale electron microscopy (EM) datasets push storage, transfer, and downstream analysis toward their current limits. We present a vector-quantized variational autoencoder-based (VQ-VAE) compression framework for EM that spans 16x to 1024x and enables pay-as-you-decode usage: top-only decoding for extreme compression, with an optional Transformer prior that predicts bottom tokens (without changing the compression ratio) to restore texture via feature-wise linear modulation (FiLM) and concatenation; we further introduce an ROI-driven workflow that performs selective high-resolution reconstruction from 1024x-compressed latents only where needed.
format Preprint
id arxiv_https___arxiv_org_abs_2511_00231
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Towards 1000-fold Electron Microscopy Image Compression for Connectomics via VQ-VAE with Transformer Prior
Yang, Fuming
Li, Yicong
Pfister, Hanspeter
Lichtman, Jeff W.
Meirovitch, Yaron
Computer Vision and Pattern Recognition
Petascale electron microscopy (EM) datasets push storage, transfer, and downstream analysis toward their current limits. We present a vector-quantized variational autoencoder-based (VQ-VAE) compression framework for EM that spans 16x to 1024x and enables pay-as-you-decode usage: top-only decoding for extreme compression, with an optional Transformer prior that predicts bottom tokens (without changing the compression ratio) to restore texture via feature-wise linear modulation (FiLM) and concatenation; we further introduce an ROI-driven workflow that performs selective high-resolution reconstruction from 1024x-compressed latents only where needed.
title Towards 1000-fold Electron Microscopy Image Compression for Connectomics via VQ-VAE with Transformer Prior
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2511.00231