Bubble damping of non-stationary oscillatory flow stabilization in microfluidic systems

Fuente: arXiv
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Autor principal: Benavent-Claró, Andreu
Formato: Preprint
Publicado: 2025
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author Benavent-Claró, Andreu
author_facet Benavent-Claró, Andreu
contents The inherent instability of oscillatory flows presents a significant challenge in microfluidics, impairing performance in different applications from particle detachemnt to organs-on-a-chip. Trapped air inside a microfluidic system passively dampens these fluctuations because of the compressible nature of air. However, a foundational theoretical model that describes this effect has remained elusive. Here, a first-principles model that fully characterizes the effects of a trapped air volume in oscillatory microfluidic flow is derived. The model identifies a dimensionless product as the governing parameter, unifying the interplay between air compressibility and fluidic resistance. It precisely predicts the volume displacement dynamics of the liquid front, which compared with the original flow, it presents amplitude reduction, phase shift, and transient drift. The theoretical framework was validated with different experiments across a broad range of conditions. This work transforms trapped air from a source of unpredictability into a powerful, predictable element for tailoring oscillatory flow stability, providing a rigorous design tool for microfluidic systems.
format Preprint
id arxiv_https___arxiv_org_abs_2511_00539
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Bubble damping of non-stationary oscillatory flow stabilization in microfluidic systems
Benavent-Claró, Andreu
Fluid Dynamics
Soft Condensed Matter
The inherent instability of oscillatory flows presents a significant challenge in microfluidics, impairing performance in different applications from particle detachemnt to organs-on-a-chip. Trapped air inside a microfluidic system passively dampens these fluctuations because of the compressible nature of air. However, a foundational theoretical model that describes this effect has remained elusive. Here, a first-principles model that fully characterizes the effects of a trapped air volume in oscillatory microfluidic flow is derived. The model identifies a dimensionless product as the governing parameter, unifying the interplay between air compressibility and fluidic resistance. It precisely predicts the volume displacement dynamics of the liquid front, which compared with the original flow, it presents amplitude reduction, phase shift, and transient drift. The theoretical framework was validated with different experiments across a broad range of conditions. This work transforms trapped air from a source of unpredictability into a powerful, predictable element for tailoring oscillatory flow stability, providing a rigorous design tool for microfluidic systems.
title Bubble damping of non-stationary oscillatory flow stabilization in microfluidic systems
topic Fluid Dynamics
Soft Condensed Matter
url https://arxiv.org/abs/2511.00539