Anatomically Constrained Transformers for Echocardiogram Analysis

Fuente: arXiv
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Main Authors: Thorley, Alexander, Chartsias, Agis, Strom, Jordan, Slivnick, Jeremy, Kotecha, Dipak, Gomez, Alberto, Duan, Jinming
Format: Preprint
Published: 2025
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author Thorley, Alexander
Chartsias, Agis
Strom, Jordan
Slivnick, Jeremy
Kotecha, Dipak
Gomez, Alberto
Duan, Jinming
author_facet Thorley, Alexander
Chartsias, Agis
Strom, Jordan
Slivnick, Jeremy
Kotecha, Dipak
Gomez, Alberto
Duan, Jinming
contents Video transformers have recently demonstrated strong potential for echocardiogram (echo) analysis, leveraging self-supervised pre-training and flexible adaptation across diverse tasks. However, like other models operating on videos, they are prone to learning spurious correlations from non-diagnostic regions such as image backgrounds. To overcome this limitation, we propose the Video Anatomically Constrained Transformer (ViACT), a novel framework that integrates anatomical priors directly into the transformer architecture. ViACT represents a deforming anatomical structure as a point set and encodes both its spatial geometry and corresponding image patches into transformer tokens. During pre-training, ViACT follows a masked autoencoding strategy that masks and reconstructs only anatomical patches, enforcing that representation learning is focused on the anatomical region. The pre-trained model can then be fine-tuned for tasks localized to this region. In this work we focus on the myocardium, demonstrating the framework on echo analysis tasks such as left ventricular ejection fraction (EF) regression and cardiac amyloidosis (CA) detection. The anatomical constraint focuses transformer attention within the myocardium, yielding interpretable attention maps aligned with regions of known CA pathology. Moreover, ViACT generalizes to myocardium point tracking without requiring task-specific components such as correlation volumes used in specialized tracking networks.
format Preprint
id arxiv_https___arxiv_org_abs_2511_01109
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Anatomically Constrained Transformers for Echocardiogram Analysis
Thorley, Alexander
Chartsias, Agis
Strom, Jordan
Slivnick, Jeremy
Kotecha, Dipak
Gomez, Alberto
Duan, Jinming
Computer Vision and Pattern Recognition
Video transformers have recently demonstrated strong potential for echocardiogram (echo) analysis, leveraging self-supervised pre-training and flexible adaptation across diverse tasks. However, like other models operating on videos, they are prone to learning spurious correlations from non-diagnostic regions such as image backgrounds. To overcome this limitation, we propose the Video Anatomically Constrained Transformer (ViACT), a novel framework that integrates anatomical priors directly into the transformer architecture. ViACT represents a deforming anatomical structure as a point set and encodes both its spatial geometry and corresponding image patches into transformer tokens. During pre-training, ViACT follows a masked autoencoding strategy that masks and reconstructs only anatomical patches, enforcing that representation learning is focused on the anatomical region. The pre-trained model can then be fine-tuned for tasks localized to this region. In this work we focus on the myocardium, demonstrating the framework on echo analysis tasks such as left ventricular ejection fraction (EF) regression and cardiac amyloidosis (CA) detection. The anatomical constraint focuses transformer attention within the myocardium, yielding interpretable attention maps aligned with regions of known CA pathology. Moreover, ViACT generalizes to myocardium point tracking without requiring task-specific components such as correlation volumes used in specialized tracking networks.
title Anatomically Constrained Transformers for Echocardiogram Analysis
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2511.01109