The impact of nonheritable variation in division rates on population growth across environments
Fuente:
arXiv
Gespeichert in:
| Hauptverfasser: | , , |
|---|---|
| Format: | Preprint |
| Veröffentlicht: |
2025
|
| Schlagworte: | |
| Online-Zugang: | |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| _version_ | 1866912686607958016 |
|---|---|
| author | Mackenzie, John A. Hillman, Adam Gomes, M. Gabriela M. |
| author_facet | Mackenzie, John A. Hillman, Adam Gomes, M. Gabriela M. |
| contents | We analyse a series of bacterial growth models with in-built inter-individual variation in rates of cell division. We show that this variation leads to reduced population growth in favorable regimes and reduced population killing in detrimental environments. By treating environmental stress as a model parameter, we then show that the reduction in population growth aggravates with stress. We apply these models to data on growth rates for populations of green algae {\em Clamydomonas reinhardtii}. Specifically, we compare growth rates of two ancestral strains and respective mutation accumulation lines, measured along a stress gradient. The data had previously shown mutants growing consistently slower than ancestors, and this effect aggravating with stress. Here we show that this trend is expected if mutants are more variable than ancestors in individual rates of cell division, even if their means are higher. This can open new prospects for prediction of how populations respond to environmental changes. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2511_01905 |
| institution | arXiv |
| publishDate | 2025 |
| record_format | arxiv |
| spellingShingle | The impact of nonheritable variation in division rates on population growth across environments Mackenzie, John A. Hillman, Adam Gomes, M. Gabriela M. Populations and Evolution We analyse a series of bacterial growth models with in-built inter-individual variation in rates of cell division. We show that this variation leads to reduced population growth in favorable regimes and reduced population killing in detrimental environments. By treating environmental stress as a model parameter, we then show that the reduction in population growth aggravates with stress. We apply these models to data on growth rates for populations of green algae {\em Clamydomonas reinhardtii}. Specifically, we compare growth rates of two ancestral strains and respective mutation accumulation lines, measured along a stress gradient. The data had previously shown mutants growing consistently slower than ancestors, and this effect aggravating with stress. Here we show that this trend is expected if mutants are more variable than ancestors in individual rates of cell division, even if their means are higher. This can open new prospects for prediction of how populations respond to environmental changes. |
| title | The impact of nonheritable variation in division rates on population growth across environments |
| topic | Populations and Evolution |
| url | https://arxiv.org/abs/2511.01905 |