A Joint Variational Framework for Multimodal X-ray Ptychography and Fluorescence Reconstruction

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Main Authors: Zou, Chengru Eric, Buser, Elle, Di, Zichao Wendy, Xi, Yuanzhe
Format: Preprint
Published: 2025
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author Zou, Chengru Eric
Buser, Elle
Di, Zichao Wendy
Xi, Yuanzhe
author_facet Zou, Chengru Eric
Buser, Elle
Di, Zichao Wendy
Xi, Yuanzhe
contents Recovering high-resolution structural and compositional information from coherent X-ray measurements involves solving coupled, nonlinear, and ill-posed inverse problems. Ptychography reconstructs a complex transmission function from overlapping diffraction patterns, while X-ray fluorescence provides quantitative, element-specific contrast at lower spatial resolution. We formulate a joint variational framework that integrates these two modalities into a single nonlinear least-squares problem with shared spatial variables. This formulation enforces cross-modal consistency between structural and compositional estimates, improving conditioning and promoting stable convergence. The resulting optimization couples complementary contrast mechanisms (i.e., phase and absorption from ptychography, elemental composition from fluorescence) within a unified inverse model. Numerical experiments on simulated data demonstrate that the joint reconstruction achieves faster convergence, sharper and more quantitative reconstructions, and lower relative error compared with separate inversions. The proposed approach illustrates how multimodal variational formulations can enhance stability, resolution, and interpretability in computational X-ray imaging.
format Preprint
id arxiv_https___arxiv_org_abs_2511_02153
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle A Joint Variational Framework for Multimodal X-ray Ptychography and Fluorescence Reconstruction
Zou, Chengru Eric
Buser, Elle
Di, Zichao Wendy
Xi, Yuanzhe
Numerical Analysis
Optimization and Control
Recovering high-resolution structural and compositional information from coherent X-ray measurements involves solving coupled, nonlinear, and ill-posed inverse problems. Ptychography reconstructs a complex transmission function from overlapping diffraction patterns, while X-ray fluorescence provides quantitative, element-specific contrast at lower spatial resolution. We formulate a joint variational framework that integrates these two modalities into a single nonlinear least-squares problem with shared spatial variables. This formulation enforces cross-modal consistency between structural and compositional estimates, improving conditioning and promoting stable convergence. The resulting optimization couples complementary contrast mechanisms (i.e., phase and absorption from ptychography, elemental composition from fluorescence) within a unified inverse model. Numerical experiments on simulated data demonstrate that the joint reconstruction achieves faster convergence, sharper and more quantitative reconstructions, and lower relative error compared with separate inversions. The proposed approach illustrates how multimodal variational formulations can enhance stability, resolution, and interpretability in computational X-ray imaging.
title A Joint Variational Framework for Multimodal X-ray Ptychography and Fluorescence Reconstruction
topic Numerical Analysis
Optimization and Control
url https://arxiv.org/abs/2511.02153