Temporal filtered quantum sensing with the nitrogen-vacancy center in diamond

Fuente: arXiv
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Main Authors: Boehm, Florian, Liu, Yan, Yue, Chengliang, Dong, Xianqi, Zhou, Huaxue, Wu, Dong, Wu, E, Yang, Renfu
Format: Preprint
Published: 2025
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author Boehm, Florian
Liu, Yan
Yue, Chengliang
Dong, Xianqi
Zhou, Huaxue
Wu, Dong
Wu, E
Yang, Renfu
author_facet Boehm, Florian
Liu, Yan
Yue, Chengliang
Dong, Xianqi
Zhou, Huaxue
Wu, Dong
Wu, E
Yang, Renfu
contents Nitrogen vacancy centers in diamond are among the leading solid state quantum platforms, offering exceptional spatial resolution and sensitivity for applications such as magnetic field sensing, thermometry, and bioimaging. However, in high background environments,such as those encountered in in vitro diagnostics, the performance of NV based sensors can be compromised by strong background fluorescence, particularly from substrates such as nitrocellulose. In this work, we analytically and experimentally investigate the use of pulsed laser excitation combined with time gating techniques to suppress background fluorescence and enhance the signal to noise ratio in NV based quantum sensing, with an emphasis on spin enhanced biosensing. Through experimental studies using mixed ensembles of silicon vacancy and NV centers in bulk diamond, as well as fluorescent nanodiamonds on NC substrates, we demonstrate significant improvements in NV spin resonance visibility, demonstrated by an increase of the SNR by up to 4x, and a resulting measurement time reduction by 16x. The presented technique and results here can help significantly increase the readout efficiency and speed in future applications of NV centers in high background environments, such as in IVD, where the NV centers are used as a fluorescent label for biomolecules.
format Preprint
id arxiv_https___arxiv_org_abs_2511_02369
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Temporal filtered quantum sensing with the nitrogen-vacancy center in diamond
Boehm, Florian
Liu, Yan
Yue, Chengliang
Dong, Xianqi
Zhou, Huaxue
Wu, Dong
Wu, E
Yang, Renfu
Quantum Physics
Applied Physics
Optics
Nitrogen vacancy centers in diamond are among the leading solid state quantum platforms, offering exceptional spatial resolution and sensitivity for applications such as magnetic field sensing, thermometry, and bioimaging. However, in high background environments,such as those encountered in in vitro diagnostics, the performance of NV based sensors can be compromised by strong background fluorescence, particularly from substrates such as nitrocellulose. In this work, we analytically and experimentally investigate the use of pulsed laser excitation combined with time gating techniques to suppress background fluorescence and enhance the signal to noise ratio in NV based quantum sensing, with an emphasis on spin enhanced biosensing. Through experimental studies using mixed ensembles of silicon vacancy and NV centers in bulk diamond, as well as fluorescent nanodiamonds on NC substrates, we demonstrate significant improvements in NV spin resonance visibility, demonstrated by an increase of the SNR by up to 4x, and a resulting measurement time reduction by 16x. The presented technique and results here can help significantly increase the readout efficiency and speed in future applications of NV centers in high background environments, such as in IVD, where the NV centers are used as a fluorescent label for biomolecules.
title Temporal filtered quantum sensing with the nitrogen-vacancy center in diamond
topic Quantum Physics
Applied Physics
Optics
url https://arxiv.org/abs/2511.02369