Unlocking n-alk-1-ynes Conformers: Quantum "Trigger Finger" versus "Stiff Joint" Conformations

Fuente: arXiv
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Main Author: Bâldea, Ioan
Format: Preprint
Published: 2025
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author Bâldea, Ioan
author_facet Bâldea, Ioan
contents Molecular conformation in n-alk-1-ynes (CnA) is conventionally simplified to an all-planar structure. We report a comprehensive quantum chemical analysis revealing two near-isoenergetic rotamers at the acetylenic terminus: planar (C$_s$) and skewed (C$_1$). The high, symmetric rotational energy barrier ($\approx 150$\,meV) arises from unique steric relief near the $\mathrm{sp}$ center coupled with electronic stabilization of C$_1$. This creates a unique kinetic profile: a Quantum ``Trigger Finger'' ($α$ rotation) that enforces an $\approx 50\%:\,50\%$ $\mathrm{C}_s/\mathrm{C}_1$ ensemble, sharply contrasting with the thermodynamically biased ``Stiff Joint'' ($δ$ rotation) of the alkyl chain. This structural degeneracy necessitates ensemble averaging for spectroscopic data interpretation, while the slow interconversion permits kinetic trapping and intentional conformer enrichment during synthesis and molecular junction fabrication. Our work redefines the alkyne anchor, providing a blueprint for accurate interpretation of spectroscopic data and achieving conformational control in molecular electronics.
format Preprint
id arxiv_https___arxiv_org_abs_2511_02470
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Unlocking n-alk-1-ynes Conformers: Quantum "Trigger Finger" versus "Stiff Joint" Conformations
Bâldea, Ioan
Chemical Physics
Mesoscale and Nanoscale Physics
Materials Science
Atomic and Molecular Clusters
Quantum Physics
Molecular conformation in n-alk-1-ynes (CnA) is conventionally simplified to an all-planar structure. We report a comprehensive quantum chemical analysis revealing two near-isoenergetic rotamers at the acetylenic terminus: planar (C$_s$) and skewed (C$_1$). The high, symmetric rotational energy barrier ($\approx 150$\,meV) arises from unique steric relief near the $\mathrm{sp}$ center coupled with electronic stabilization of C$_1$. This creates a unique kinetic profile: a Quantum ``Trigger Finger'' ($α$ rotation) that enforces an $\approx 50\%:\,50\%$ $\mathrm{C}_s/\mathrm{C}_1$ ensemble, sharply contrasting with the thermodynamically biased ``Stiff Joint'' ($δ$ rotation) of the alkyl chain. This structural degeneracy necessitates ensemble averaging for spectroscopic data interpretation, while the slow interconversion permits kinetic trapping and intentional conformer enrichment during synthesis and molecular junction fabrication. Our work redefines the alkyne anchor, providing a blueprint for accurate interpretation of spectroscopic data and achieving conformational control in molecular electronics.
title Unlocking n-alk-1-ynes Conformers: Quantum "Trigger Finger" versus "Stiff Joint" Conformations
topic Chemical Physics
Mesoscale and Nanoscale Physics
Materials Science
Atomic and Molecular Clusters
Quantum Physics
url https://arxiv.org/abs/2511.02470