Domain-Adaptive Transformer for Data-Efficient Glioma Segmentation in Sub-Saharan MRI

Fuente: arXiv
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Main Authors: Abolade, Ilerioluwakiiye, Udo, Aniekan, Ojo, Augustine, Oyetunji, Abdulbasit, Ajigbotosho, Hammed, Iorumbur, Aondana, Raymond, Confidence, Adewole, Maruf
Format: Preprint
Published: 2025
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author Abolade, Ilerioluwakiiye
Udo, Aniekan
Ojo, Augustine
Oyetunji, Abdulbasit
Ajigbotosho, Hammed
Iorumbur, Aondana
Raymond, Confidence
Adewole, Maruf
author_facet Abolade, Ilerioluwakiiye
Udo, Aniekan
Ojo, Augustine
Oyetunji, Abdulbasit
Ajigbotosho, Hammed
Iorumbur, Aondana
Raymond, Confidence
Adewole, Maruf
contents Glioma segmentation is critical for diagnosis and treatment planning, yet remains challenging in Sub-Saharan Africa due to limited MRI infrastructure and heterogeneous acquisition protocols that induce severe domain shift. We propose SegFormer3D-plus, a radiomics-guided transformer architecture designed for robust segmentation under domain variability. Our method combines: (1) histogram matching for intensity harmonization across scanners, (2) radiomic feature extraction with PCA-reduced k-means for domain-aware stratified sampling, (3) a dual-pathway encoder with frequency-aware feature extraction and spatial-channel attention, and (4) composite Dice-Cross-Entropy loss for boundary refinement. Pretrained on BraTS 2023 and fine-tuned on BraTS-Africa data, SegFormer3D-plus demonstrates improved tumor subregion delineation and boundary localization across heterogeneous African clinical scans, highlighting the value of radiomics-guided domain adaptation for resource-limited settings.
format Preprint
id arxiv_https___arxiv_org_abs_2511_02928
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Domain-Adaptive Transformer for Data-Efficient Glioma Segmentation in Sub-Saharan MRI
Abolade, Ilerioluwakiiye
Udo, Aniekan
Ojo, Augustine
Oyetunji, Abdulbasit
Ajigbotosho, Hammed
Iorumbur, Aondana
Raymond, Confidence
Adewole, Maruf
Image and Video Processing
Computer Vision and Pattern Recognition
I.2.10; I.4.8; J.3
Glioma segmentation is critical for diagnosis and treatment planning, yet remains challenging in Sub-Saharan Africa due to limited MRI infrastructure and heterogeneous acquisition protocols that induce severe domain shift. We propose SegFormer3D-plus, a radiomics-guided transformer architecture designed for robust segmentation under domain variability. Our method combines: (1) histogram matching for intensity harmonization across scanners, (2) radiomic feature extraction with PCA-reduced k-means for domain-aware stratified sampling, (3) a dual-pathway encoder with frequency-aware feature extraction and spatial-channel attention, and (4) composite Dice-Cross-Entropy loss for boundary refinement. Pretrained on BraTS 2023 and fine-tuned on BraTS-Africa data, SegFormer3D-plus demonstrates improved tumor subregion delineation and boundary localization across heterogeneous African clinical scans, highlighting the value of radiomics-guided domain adaptation for resource-limited settings.
title Domain-Adaptive Transformer for Data-Efficient Glioma Segmentation in Sub-Saharan MRI
topic Image and Video Processing
Computer Vision and Pattern Recognition
I.2.10; I.4.8; J.3
url https://arxiv.org/abs/2511.02928