Centralized Health and Exposomic Resource (C-HER): Analytic and AI-Ready Data for External Exposomic Research

Fuente: arXiv
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Main Authors: Hanson, Heidi A., Ramsay, Joemy, Grant, Josh, Davis, Maggie, Agbaje, Janet O., Maguire, Dakotah, Logan, Jeremy, Taddie, Marissa, Melton, Chad, MacFarland, Midgie, VanDerslice, James
Format: Preprint
Published: 2025
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author Hanson, Heidi A.
Ramsay, Joemy
Grant, Josh
Davis, Maggie
Agbaje, Janet O.
Maguire, Dakotah
Logan, Jeremy
Taddie, Marissa
Melton, Chad
MacFarland, Midgie
VanDerslice, James
author_facet Hanson, Heidi A.
Ramsay, Joemy
Grant, Josh
Davis, Maggie
Agbaje, Janet O.
Maguire, Dakotah
Logan, Jeremy
Taddie, Marissa
Melton, Chad
MacFarland, Midgie
VanDerslice, James
contents The Centralized Health and Exposomic Resource (C-HER) project has identified, profiled, spatially indexed, and stored over 30 external exposomic datasets. The resulting analytic and AI-ready data (AAIRD) provides a significant opportunity to develop an integrated picture of the exposome for health research. The exposome is a conceptual framework designed to guide the study of the complex environmental and genetic factors that together shape human health. Few composite measures of the exposome exist due to the high dimensionality of exposure data, multimodal data sources, and varying spatiotemporal scales. We develop a data engineering solution that overcomes the challenges of spatio-temporal linkage in this field. We provide examples of how environmental data can be combined to characterize a region, model air pollution, or provide indicators for cancer research. The development of AAIRD will allow future studies to use ML and deep learning methods to generate spatial and contextual exposure data for disease prediction.
format Preprint
id arxiv_https___arxiv_org_abs_2511_03750
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Centralized Health and Exposomic Resource (C-HER): Analytic and AI-Ready Data for External Exposomic Research
Hanson, Heidi A.
Ramsay, Joemy
Grant, Josh
Davis, Maggie
Agbaje, Janet O.
Maguire, Dakotah
Logan, Jeremy
Taddie, Marissa
Melton, Chad
MacFarland, Midgie
VanDerslice, James
Applications
The Centralized Health and Exposomic Resource (C-HER) project has identified, profiled, spatially indexed, and stored over 30 external exposomic datasets. The resulting analytic and AI-ready data (AAIRD) provides a significant opportunity to develop an integrated picture of the exposome for health research. The exposome is a conceptual framework designed to guide the study of the complex environmental and genetic factors that together shape human health. Few composite measures of the exposome exist due to the high dimensionality of exposure data, multimodal data sources, and varying spatiotemporal scales. We develop a data engineering solution that overcomes the challenges of spatio-temporal linkage in this field. We provide examples of how environmental data can be combined to characterize a region, model air pollution, or provide indicators for cancer research. The development of AAIRD will allow future studies to use ML and deep learning methods to generate spatial and contextual exposure data for disease prediction.
title Centralized Health and Exposomic Resource (C-HER): Analytic and AI-Ready Data for External Exposomic Research
topic Applications
url https://arxiv.org/abs/2511.03750