Mathematical and Computational Nuclear Oncology: Toward Optimized Radiopharmaceutical Therapy via Digital Twins

Fuente: arXiv
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Autores principales: Ryhiner, Marc, Song, Yangmeihui, Saboury, Babak, Glatting, Gerhard, Rahmim, Arman, Shi, Kuangyu
Formato: Preprint
Publicado: 2025
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author Ryhiner, Marc
Song, Yangmeihui
Saboury, Babak
Glatting, Gerhard
Rahmim, Arman
Shi, Kuangyu
author_facet Ryhiner, Marc
Song, Yangmeihui
Saboury, Babak
Glatting, Gerhard
Rahmim, Arman
Shi, Kuangyu
contents This article presents the general framework of theranostic digital twins (TDTs) in computational nuclear medicine, designed to support clinical decision-making and improve cancer patient prognosis through personalized radiopharmaceutical therapies (RPTs). It outlines potential clinical applications of TDTs and proposes a roadmap for successful implementation. Additionally, the chapter provides a conceptual overview of the current state of the art in the mathematical and computational modeling of RPTs, highlighting key challenges and the strategies being pursued to address them.
format Preprint
id arxiv_https___arxiv_org_abs_2511_03755
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Mathematical and Computational Nuclear Oncology: Toward Optimized Radiopharmaceutical Therapy via Digital Twins
Ryhiner, Marc
Song, Yangmeihui
Saboury, Babak
Glatting, Gerhard
Rahmim, Arman
Shi, Kuangyu
Other Quantitative Biology
This article presents the general framework of theranostic digital twins (TDTs) in computational nuclear medicine, designed to support clinical decision-making and improve cancer patient prognosis through personalized radiopharmaceutical therapies (RPTs). It outlines potential clinical applications of TDTs and proposes a roadmap for successful implementation. Additionally, the chapter provides a conceptual overview of the current state of the art in the mathematical and computational modeling of RPTs, highlighting key challenges and the strategies being pursued to address them.
title Mathematical and Computational Nuclear Oncology: Toward Optimized Radiopharmaceutical Therapy via Digital Twins
topic Other Quantitative Biology
url https://arxiv.org/abs/2511.03755