Left Atrial Segmentation with nnU-Net Using MRI

Fuente: arXiv
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Auteurs principaux: Hosseinabadi, Fatemeh, Sharifi, Seyedhassan
Format: Preprint
Publié: 2025
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author Hosseinabadi, Fatemeh
Sharifi, Seyedhassan
author_facet Hosseinabadi, Fatemeh
Sharifi, Seyedhassan
contents Accurate segmentation of the left atrium (LA) from cardiac MRI is critical for guiding atrial fibrillation (AF) ablation and constructing biophysical cardiac models. Manual delineation is time-consuming, observer-dependent, and impractical for large-scale or time-sensitive clinical workflows. Deep learning methods, particularly convolutional architectures, have recently demonstrated superior performance in medical image segmentation tasks. In this study, we applied the nnU-Net framework, an automated, self-configuring deep learning segmentation architecture, to the Left Atrial Segmentation Challenge 2013 dataset. The dataset consists of thirty MRI scans with corresponding expert-annotated masks. The nnU-Net model automatically adapted its preprocessing, network configuration, and training pipeline to the characteristics of the MRI data. Model performance was quantitatively evaluated using the Dice similarity coefficient (DSC), and qualitative results were compared against expert segmentations. The proposed nnUNet model achieved a mean Dice score of 93.5, demonstrating high overlap with expert annotations and outperforming several traditional segmentation approaches reported in previous studies. The network exhibited robust generalization across variations in left atrial shape, contrast, and image quality, accurately delineating both the atrial body and proximal pulmonary veins.
format Preprint
id arxiv_https___arxiv_org_abs_2511_04071
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Left Atrial Segmentation with nnU-Net Using MRI
Hosseinabadi, Fatemeh
Sharifi, Seyedhassan
Image and Video Processing
Artificial Intelligence
Machine Learning
Accurate segmentation of the left atrium (LA) from cardiac MRI is critical for guiding atrial fibrillation (AF) ablation and constructing biophysical cardiac models. Manual delineation is time-consuming, observer-dependent, and impractical for large-scale or time-sensitive clinical workflows. Deep learning methods, particularly convolutional architectures, have recently demonstrated superior performance in medical image segmentation tasks. In this study, we applied the nnU-Net framework, an automated, self-configuring deep learning segmentation architecture, to the Left Atrial Segmentation Challenge 2013 dataset. The dataset consists of thirty MRI scans with corresponding expert-annotated masks. The nnU-Net model automatically adapted its preprocessing, network configuration, and training pipeline to the characteristics of the MRI data. Model performance was quantitatively evaluated using the Dice similarity coefficient (DSC), and qualitative results were compared against expert segmentations. The proposed nnUNet model achieved a mean Dice score of 93.5, demonstrating high overlap with expert annotations and outperforming several traditional segmentation approaches reported in previous studies. The network exhibited robust generalization across variations in left atrial shape, contrast, and image quality, accurately delineating both the atrial body and proximal pulmonary veins.
title Left Atrial Segmentation with nnU-Net Using MRI
topic Image and Video Processing
Artificial Intelligence
Machine Learning
url https://arxiv.org/abs/2511.04071