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| Main Authors: | , , , , , , , , , , , , , , , , |
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| Format: | Preprint |
| Published: |
2025
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| Subjects: | |
| Online Access: | https://arxiv.org/abs/2511.04262 |
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| _version_ | 1866911251307692032 |
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| author | Mörth, Eric Turner, Morgan L. Nielsen, Cydney Liu, Xianhao Carton Keller, Mark Choy, Lisa Conroy, John Kakar, Tabassum Yapp, Clarence Wong, Alex Sorger, Peter McLaughlin, Liam Jain, Sanjay Beyer, Johanna Pfister, Hanspeter Zhu-Tian, Chen Gehlenborg, Nils |
| author_facet | Mörth, Eric Turner, Morgan L. Nielsen, Cydney Liu, Xianhao Carton Keller, Mark Choy, Lisa Conroy, John Kakar, Tabassum Yapp, Clarence Wong, Alex Sorger, Peter McLaughlin, Liam Jain, Sanjay Beyer, Johanna Pfister, Hanspeter Zhu-Tian, Chen Gehlenborg, Nils |
| contents | Advances in spatial omics and high-resolution imaging enable the creation of three-dimensional (3D) tissue maps that capture cellular organization and interactions in situ. While these data provide critical insights into tissue function and disease, their exploration is often constrained by tools limited to 2D displays or stereoscopic rendering without analytical integration. We present Vitessce Link, a web-based hybrid framework that unites a 3D stereoscopic view in mixed reality with a synchronized 2D display environment. Users can navigate volumetric data with intuitive hand gestures while controlling channels, filters, and derived data views through the Vitessce platform. Built on open standards and running entirely in the browser, Vitessce Link minimizes friction, supports integration with computational notebooks, and synchronizes interactions across devices via a lightweight WebSocket architecture. Case studies in nephrology and oncology demonstrate how the hybrid approach enhances segmentation evaluation, distance measurement, and interpretation of spatial relationships. Vitessce Link establishes a paradigm for integrative, web-native analysis of 3D tissue maps. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2511_04262 |
| institution | arXiv |
| publishDate | 2025 |
| record_format | arxiv |
| spellingShingle | Vitessce Link: A Mixed Reality and 2D Display Hybrid Approach for Visual Analysis of 3D Tissue Maps Mörth, Eric Turner, Morgan L. Nielsen, Cydney Liu, Xianhao Carton Keller, Mark Choy, Lisa Conroy, John Kakar, Tabassum Yapp, Clarence Wong, Alex Sorger, Peter McLaughlin, Liam Jain, Sanjay Beyer, Johanna Pfister, Hanspeter Zhu-Tian, Chen Gehlenborg, Nils Human-Computer Interaction Advances in spatial omics and high-resolution imaging enable the creation of three-dimensional (3D) tissue maps that capture cellular organization and interactions in situ. While these data provide critical insights into tissue function and disease, their exploration is often constrained by tools limited to 2D displays or stereoscopic rendering without analytical integration. We present Vitessce Link, a web-based hybrid framework that unites a 3D stereoscopic view in mixed reality with a synchronized 2D display environment. Users can navigate volumetric data with intuitive hand gestures while controlling channels, filters, and derived data views through the Vitessce platform. Built on open standards and running entirely in the browser, Vitessce Link minimizes friction, supports integration with computational notebooks, and synchronizes interactions across devices via a lightweight WebSocket architecture. Case studies in nephrology and oncology demonstrate how the hybrid approach enhances segmentation evaluation, distance measurement, and interpretation of spatial relationships. Vitessce Link establishes a paradigm for integrative, web-native analysis of 3D tissue maps. |
| title | Vitessce Link: A Mixed Reality and 2D Display Hybrid Approach for Visual Analysis of 3D Tissue Maps |
| topic | Human-Computer Interaction |
| url | https://arxiv.org/abs/2511.04262 |