Making Knowledge Accessible: Divergent Readability-Accuracy Strategies of Mistral and QWen in Biomedical Text Simplification

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Autori principali: Githinji, P. Bilha, Melliou, Aikaterini, Liang, Zeming, Zhang, Lian, Qin, Peiwu
Natura: Preprint
Pubblicazione: 2025
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author Githinji, P. Bilha
Melliou, Aikaterini
Liang, Zeming
Zhang, Lian
Qin, Peiwu
author_facet Githinji, P. Bilha
Melliou, Aikaterini
Liang, Zeming
Zhang, Lian
Qin, Peiwu
contents The growing public demand for accessible biomedical information calls for scalable text simplification. While large language models (LLMs) offer solutions, they too struggle with balancing improved readability against preservation of meaning. This report empirically compares how two LLMs - instruction-tuned Mistral-Small 3 24B and the reasoning-augmented QWen2.5 32B- navigate this trade-off in biomedical text simplification, benchmarked against human performance. Our analysis highlights how each model applies distinct operational strategies when simplifying biomedical text. Mistral exhibits a tempered lexical simplification approach that consistently enhances readability across multiple metrics while preserving discourse fidelity (BERTScore: 0.91, statistically comparable to that of humans). In comparison, QWen also attains enhanced readability performance and a reasonable BERTScore of 0.89, but presents a disconnect in balancing between readability and accuracy. Additionally, a comprehensive correlation analysis of a suite of 21 metrics confirms strong functional redundancies in metrics and informs adaptation requirements.
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publishDate 2025
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spellingShingle Making Knowledge Accessible: Divergent Readability-Accuracy Strategies of Mistral and QWen in Biomedical Text Simplification
Githinji, P. Bilha
Melliou, Aikaterini
Liang, Zeming
Zhang, Lian
Qin, Peiwu
Computation and Language
The growing public demand for accessible biomedical information calls for scalable text simplification. While large language models (LLMs) offer solutions, they too struggle with balancing improved readability against preservation of meaning. This report empirically compares how two LLMs - instruction-tuned Mistral-Small 3 24B and the reasoning-augmented QWen2.5 32B- navigate this trade-off in biomedical text simplification, benchmarked against human performance. Our analysis highlights how each model applies distinct operational strategies when simplifying biomedical text. Mistral exhibits a tempered lexical simplification approach that consistently enhances readability across multiple metrics while preserving discourse fidelity (BERTScore: 0.91, statistically comparable to that of humans). In comparison, QWen also attains enhanced readability performance and a reasonable BERTScore of 0.89, but presents a disconnect in balancing between readability and accuracy. Additionally, a comprehensive correlation analysis of a suite of 21 metrics confirms strong functional redundancies in metrics and informs adaptation requirements.
title Making Knowledge Accessible: Divergent Readability-Accuracy Strategies of Mistral and QWen in Biomedical Text Simplification
topic Computation and Language
url https://arxiv.org/abs/2511.05080