Beyond Plain Demos: A Demo-centric Anchoring Paradigm for In-Context Learning in Alzheimer's Disease Detection

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Hauptverfasser: Su, Puzhen, Yin, Haoran, Miao, Yongzhu, Tang, Jintao, Li, Shasha, Wang, Ting
Format: Preprint
Veröffentlicht: 2025
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author Su, Puzhen
Yin, Haoran
Miao, Yongzhu
Tang, Jintao
Li, Shasha
Wang, Ting
author_facet Su, Puzhen
Yin, Haoran
Miao, Yongzhu
Tang, Jintao
Li, Shasha
Wang, Ting
contents Detecting Alzheimer's disease (AD) from narrative transcripts challenges large language models (LLMs): pre-training rarely covers this out-of-distribution task, and all transcript demos describe the same scene, producing highly homogeneous contexts. These factors cripple both the model's built-in task knowledge (\textbf{task cognition}) and its ability to surface subtle, class-discriminative cues (\textbf{contextual perception}). Because cognition is fixed after pre-training, improving in-context learning (ICL) for AD detection hinges on enriching perception through better demonstration (demo) sets. We demonstrate that standard ICL quickly saturates, its demos lack diversity (context width) and fail to convey fine-grained signals (context depth), and that recent task vector (TV) approaches improve broad task adaptation by injecting TV into the LLMs' hidden states (HSs), they are ill-suited for AD detection due to the mismatch of injection granularity, strength and position. To address these bottlenecks, we introduce \textbf{DA4ICL}, a demo-centric anchoring framework that jointly expands context width via \emph{\textbf{Diverse and Contrastive Retrieval}} (DCR) and deepens each demo's signal via \emph{\textbf{Projected Vector Anchoring}} (PVA) at every Transformer layer. Across three AD benchmarks, DA4ICL achieves large, stable gains over both ICL and TV baselines, charting a new paradigm for fine-grained, OOD and low-resource LLM adaptation.
format Preprint
id arxiv_https___arxiv_org_abs_2511_06826
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Beyond Plain Demos: A Demo-centric Anchoring Paradigm for In-Context Learning in Alzheimer's Disease Detection
Su, Puzhen
Yin, Haoran
Miao, Yongzhu
Tang, Jintao
Li, Shasha
Wang, Ting
Computation and Language
Artificial Intelligence
Detecting Alzheimer's disease (AD) from narrative transcripts challenges large language models (LLMs): pre-training rarely covers this out-of-distribution task, and all transcript demos describe the same scene, producing highly homogeneous contexts. These factors cripple both the model's built-in task knowledge (\textbf{task cognition}) and its ability to surface subtle, class-discriminative cues (\textbf{contextual perception}). Because cognition is fixed after pre-training, improving in-context learning (ICL) for AD detection hinges on enriching perception through better demonstration (demo) sets. We demonstrate that standard ICL quickly saturates, its demos lack diversity (context width) and fail to convey fine-grained signals (context depth), and that recent task vector (TV) approaches improve broad task adaptation by injecting TV into the LLMs' hidden states (HSs), they are ill-suited for AD detection due to the mismatch of injection granularity, strength and position. To address these bottlenecks, we introduce \textbf{DA4ICL}, a demo-centric anchoring framework that jointly expands context width via \emph{\textbf{Diverse and Contrastive Retrieval}} (DCR) and deepens each demo's signal via \emph{\textbf{Projected Vector Anchoring}} (PVA) at every Transformer layer. Across three AD benchmarks, DA4ICL achieves large, stable gains over both ICL and TV baselines, charting a new paradigm for fine-grained, OOD and low-resource LLM adaptation.
title Beyond Plain Demos: A Demo-centric Anchoring Paradigm for In-Context Learning in Alzheimer's Disease Detection
topic Computation and Language
Artificial Intelligence
url https://arxiv.org/abs/2511.06826