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| Auteurs principaux: | , , , , |
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| Format: | Preprint |
| Publié: |
2025
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| Sujets: | |
| Accès en ligne: | https://arxiv.org/abs/2511.07497 |
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| _version_ | 1866918194173706240 |
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| author | Frances-Abellan, Anna Endesfelder, David Hernandez, Alfredo Armengol, Gemma Barquinero, Joan Francesc |
| author_facet | Frances-Abellan, Anna Endesfelder, David Hernandez, Alfredo Armengol, Gemma Barquinero, Joan Francesc |
| contents | Purpose: Since its initial release, the aim of Biodose Tools was to offer an easy-to-use platform to perform the mathematical calculations needed in biological dosimetry. This update 3.7.1, mainly focuses on new features related to large-scale emergency responses, like criticality accidents dose estimation and laboratory networks. Material and Methods: Biodose Tools has been developed using the R programming language. The current version (3.7.1) uses the same external dependencies as version 3.6.1 (released November 2022) while integrating three new external packages to support the new functionalities. Results: Version 3.7.1 introduces different new modules: (a) a characteristic limits module that calculates decision thresholds and detection limits following ISO19238:2023 standards, and offers statistical tests to compare rates between suspected exposure cases and control data; (b) an enhanced dose estimation module which supports multiple dose assessments for dicentric and translocation assays for various exposure scenarios (acute, protracted, and highly protracted) as well as whole and partial-body exposures; (c) a criticality accidents module for multiple dose estimations using dicentrics in mixed gamma-neutron exposure scenarios (e.g., nuclear detonations); and (d) an Interlaboratory comparison module that automates the evaluation and comparison of dose estimates across laboratories. Conclusions: Biodose Tools (biodosetools.reneb.bfs.de) continues to evolve in response to the dynamic needs of the biological dosimetry community, contributing to the preparedness and consistency in emergency response and routine applications. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2511_07497 |
| institution | arXiv |
| publishDate | 2025 |
| record_format | arxiv |
| spellingShingle | Biodose Tools updates for criticality accidents and interlaboratory comparisons Frances-Abellan, Anna Endesfelder, David Hernandez, Alfredo Armengol, Gemma Barquinero, Joan Francesc Quantitative Methods Purpose: Since its initial release, the aim of Biodose Tools was to offer an easy-to-use platform to perform the mathematical calculations needed in biological dosimetry. This update 3.7.1, mainly focuses on new features related to large-scale emergency responses, like criticality accidents dose estimation and laboratory networks. Material and Methods: Biodose Tools has been developed using the R programming language. The current version (3.7.1) uses the same external dependencies as version 3.6.1 (released November 2022) while integrating three new external packages to support the new functionalities. Results: Version 3.7.1 introduces different new modules: (a) a characteristic limits module that calculates decision thresholds and detection limits following ISO19238:2023 standards, and offers statistical tests to compare rates between suspected exposure cases and control data; (b) an enhanced dose estimation module which supports multiple dose assessments for dicentric and translocation assays for various exposure scenarios (acute, protracted, and highly protracted) as well as whole and partial-body exposures; (c) a criticality accidents module for multiple dose estimations using dicentrics in mixed gamma-neutron exposure scenarios (e.g., nuclear detonations); and (d) an Interlaboratory comparison module that automates the evaluation and comparison of dose estimates across laboratories. Conclusions: Biodose Tools (biodosetools.reneb.bfs.de) continues to evolve in response to the dynamic needs of the biological dosimetry community, contributing to the preparedness and consistency in emergency response and routine applications. |
| title | Biodose Tools updates for criticality accidents and interlaboratory comparisons |
| topic | Quantitative Methods |
| url | https://arxiv.org/abs/2511.07497 |