OMOP ETL Framework for Semi-Structured Health Data

Fuente: arXiv
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Auteurs principaux: Desmond, Jacob, Wartmann, Ryan, Lau, Chng Wei, Thomas, Steven, Middleton, Paul M., Ginige, Jeewani Anupama
Format: Preprint
Publié: 2025
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author Desmond, Jacob
Wartmann, Ryan
Lau, Chng Wei
Thomas, Steven
Middleton, Paul M.
Ginige, Jeewani Anupama
author_facet Desmond, Jacob
Wartmann, Ryan
Lau, Chng Wei
Thomas, Steven
Middleton, Paul M.
Ginige, Jeewani Anupama
contents Healthcare data are generated in many different formats, which makes it difficult to integrate and reuse across institutions and studies. Standardisation is required to enable consistent large-scale analysis. The OMOP-CDM, developed by the OHDSI community, provides one widely adopted standard. Our framework achieves schema-agnostic transformation by extending upon existing literature in using human-readable YAML specification to support both relational (Microsoft SQL Server (MSSQL)) and document-based (MongoDB) data sources. It also incorporates critical production readiness features: provenance-aware mapping and support for incremental updates. We validated the pipeline using 2.7 million patient records and 27 million encounters across six hospitals spanning two decades of records. The resulting OMOP-CDM dataset demonstrated an acceptable level of data quality with a 97% overall passing rate based on the OHDSI Data Quality Dashboard check. Our work provides a reusable blueprint for large-scale data harmonisation, directly supporting real-world medical data research.
format Preprint
id arxiv_https___arxiv_org_abs_2511_09017
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle OMOP ETL Framework for Semi-Structured Health Data
Desmond, Jacob
Wartmann, Ryan
Lau, Chng Wei
Thomas, Steven
Middleton, Paul M.
Ginige, Jeewani Anupama
Quantitative Methods
Healthcare data are generated in many different formats, which makes it difficult to integrate and reuse across institutions and studies. Standardisation is required to enable consistent large-scale analysis. The OMOP-CDM, developed by the OHDSI community, provides one widely adopted standard. Our framework achieves schema-agnostic transformation by extending upon existing literature in using human-readable YAML specification to support both relational (Microsoft SQL Server (MSSQL)) and document-based (MongoDB) data sources. It also incorporates critical production readiness features: provenance-aware mapping and support for incremental updates. We validated the pipeline using 2.7 million patient records and 27 million encounters across six hospitals spanning two decades of records. The resulting OMOP-CDM dataset demonstrated an acceptable level of data quality with a 97% overall passing rate based on the OHDSI Data Quality Dashboard check. Our work provides a reusable blueprint for large-scale data harmonisation, directly supporting real-world medical data research.
title OMOP ETL Framework for Semi-Structured Health Data
topic Quantitative Methods
url https://arxiv.org/abs/2511.09017