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Autori principali: Hsieh, Yi-Hsien, Chien, Ta-Jung, Huang, Chun-Kai, Sun, Shao-Hua, Lin, Che
Natura: Preprint
Pubblicazione: 2025
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Accesso online:https://arxiv.org/abs/2511.09247
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author Hsieh, Yi-Hsien
Chien, Ta-Jung
Huang, Chun-Kai
Sun, Shao-Hua
Lin, Che
author_facet Hsieh, Yi-Hsien
Chien, Ta-Jung
Huang, Chun-Kai
Sun, Shao-Hua
Lin, Che
contents Clinical time series derived from electronic health records (EHRs) are inherently irregular, with asynchronous sampling, missing values, and heterogeneous feature dynamics. While numerical laboratory measurements are highly informative, existing embedding strategies usually combine feature identity and value embeddings through additive operations, which constrains their ability to capture value-dependent feature interactions. We propose MedFuse, a framework for irregular clinical time series centered on the MuFuse (Multiplicative Embedding Fusion) module. MuFuse fuses value and feature embeddings through multiplicative modulation, preserving feature-specific information while modeling higher-order dependencies across features. Experiments on three real-world datasets covering both intensive and chronic care show that MedFuse consistently outperforms state-of-the-art baselines on key predictive tasks. Analysis of the learned representations further demonstrates that multiplicative fusion enhances expressiveness and supports cross-dataset pretraining. These results establish MedFuse as a generalizable approach for modeling irregular clinical time series.
format Preprint
id arxiv_https___arxiv_org_abs_2511_09247
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle MedFuse: Multiplicative Embedding Fusion For Irregular Clinical Time Series
Hsieh, Yi-Hsien
Chien, Ta-Jung
Huang, Chun-Kai
Sun, Shao-Hua
Lin, Che
Artificial Intelligence
Clinical time series derived from electronic health records (EHRs) are inherently irregular, with asynchronous sampling, missing values, and heterogeneous feature dynamics. While numerical laboratory measurements are highly informative, existing embedding strategies usually combine feature identity and value embeddings through additive operations, which constrains their ability to capture value-dependent feature interactions. We propose MedFuse, a framework for irregular clinical time series centered on the MuFuse (Multiplicative Embedding Fusion) module. MuFuse fuses value and feature embeddings through multiplicative modulation, preserving feature-specific information while modeling higher-order dependencies across features. Experiments on three real-world datasets covering both intensive and chronic care show that MedFuse consistently outperforms state-of-the-art baselines on key predictive tasks. Analysis of the learned representations further demonstrates that multiplicative fusion enhances expressiveness and supports cross-dataset pretraining. These results establish MedFuse as a generalizable approach for modeling irregular clinical time series.
title MedFuse: Multiplicative Embedding Fusion For Irregular Clinical Time Series
topic Artificial Intelligence
url https://arxiv.org/abs/2511.09247