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Main Authors: Morrill, Todd, Puli, Aahlad, Megjhani, Murad, Park, Soojin, Zemel, Richard
Format: Preprint
Published: 2025
Subjects:
Online Access:https://arxiv.org/abs/2511.09567
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author Morrill, Todd
Puli, Aahlad
Megjhani, Murad
Park, Soojin
Zemel, Richard
author_facet Morrill, Todd
Puli, Aahlad
Megjhani, Murad
Park, Soojin
Zemel, Richard
contents Deep mixture-of-experts models have attracted a lot of attention for survival analysis problems, particularly for their ability to cluster similar patients together. In practice, grouping often comes at the expense of key metrics such as calibration error and predictive accuracy. This is due to the restrictive inductive bias that mixture-of-experts imposes, that predictions for individual patients must look like predictions for the group they're assigned to. Might we be able to discover patient group structure, where it exists, while improving calibration and predictive accuracy? In this work, we introduce several discrete-time deep mixture-of-experts (MoE)-based architectures for survival analysis problems, one of which achieves all desiderata: clustering, calibration, and predictive accuracy. We show that a key differentiator between this array of MoEs is how expressive their experts are. We find that more expressive experts that tailor predictions per patient outperform experts that rely on fixed group prototypes.
format Preprint
id arxiv_https___arxiv_org_abs_2511_09567
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Let the Experts Speak: Improving Survival Prediction & Calibration via Mixture-of-Experts Heads
Morrill, Todd
Puli, Aahlad
Megjhani, Murad
Park, Soojin
Zemel, Richard
Machine Learning
Deep mixture-of-experts models have attracted a lot of attention for survival analysis problems, particularly for their ability to cluster similar patients together. In practice, grouping often comes at the expense of key metrics such as calibration error and predictive accuracy. This is due to the restrictive inductive bias that mixture-of-experts imposes, that predictions for individual patients must look like predictions for the group they're assigned to. Might we be able to discover patient group structure, where it exists, while improving calibration and predictive accuracy? In this work, we introduce several discrete-time deep mixture-of-experts (MoE)-based architectures for survival analysis problems, one of which achieves all desiderata: clustering, calibration, and predictive accuracy. We show that a key differentiator between this array of MoEs is how expressive their experts are. We find that more expressive experts that tailor predictions per patient outperform experts that rely on fixed group prototypes.
title Let the Experts Speak: Improving Survival Prediction & Calibration via Mixture-of-Experts Heads
topic Machine Learning
url https://arxiv.org/abs/2511.09567