MIRNet: Integrating Constrained Graph-Based Reasoning with Pre-training for Diagnostic Medical Imaging

Fuente: arXiv
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Main Authors: Kong, Shufeng, Wang, Zijie, Cui, Nuan, Tang, Hao, Meng, Yihan, Wei, Yuanyuan, Chen, Feifan, Wang, Yingheng, Cai, Zhuo, Wang, Yaonan, Zhang, Yulong, Li, Yuzheng, Zheng, Zibin, Liu, Caihua, Liang, Hao
Format: Preprint
Published: 2025
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author Kong, Shufeng
Wang, Zijie
Cui, Nuan
Tang, Hao
Meng, Yihan
Wei, Yuanyuan
Chen, Feifan
Wang, Yingheng
Cai, Zhuo
Wang, Yaonan
Zhang, Yulong
Li, Yuzheng
Zheng, Zibin
Liu, Caihua
Liang, Hao
author_facet Kong, Shufeng
Wang, Zijie
Cui, Nuan
Tang, Hao
Meng, Yihan
Wei, Yuanyuan
Chen, Feifan
Wang, Yingheng
Cai, Zhuo
Wang, Yaonan
Zhang, Yulong
Li, Yuzheng
Zheng, Zibin
Liu, Caihua
Liang, Hao
contents Automated interpretation of medical images demands robust modeling of complex visual-semantic relationships while addressing annotation scarcity, label imbalance, and clinical plausibility constraints. We introduce MIRNet (Medical Image Reasoner Network), a novel framework that integrates self-supervised pre-training with constrained graph-based reasoning. Tongue image diagnosis is a particularly challenging domain that requires fine-grained visual and semantic understanding. Our approach leverages self-supervised masked autoencoder (MAE) to learn transferable visual representations from unlabeled data; employs graph attention networks (GAT) to model label correlations through expert-defined structured graphs; enforces clinical priors via constraint-aware optimization using KL divergence and regularization losses; and mitigates imbalance using asymmetric loss (ASL) and boosting ensembles. To address annotation scarcity, we also introduce TongueAtlas-4K, a comprehensive expert-curated benchmark comprising 4,000 images annotated with 22 diagnostic labels--representing the largest public dataset in tongue analysis. Validation shows our method achieves state-of-the-art performance. While optimized for tongue diagnosis, the framework readily generalizes to broader diagnostic medical imaging tasks.
format Preprint
id arxiv_https___arxiv_org_abs_2511_10013
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle MIRNet: Integrating Constrained Graph-Based Reasoning with Pre-training for Diagnostic Medical Imaging
Kong, Shufeng
Wang, Zijie
Cui, Nuan
Tang, Hao
Meng, Yihan
Wei, Yuanyuan
Chen, Feifan
Wang, Yingheng
Cai, Zhuo
Wang, Yaonan
Zhang, Yulong
Li, Yuzheng
Zheng, Zibin
Liu, Caihua
Liang, Hao
Computer Vision and Pattern Recognition
Artificial Intelligence
68T07
Automated interpretation of medical images demands robust modeling of complex visual-semantic relationships while addressing annotation scarcity, label imbalance, and clinical plausibility constraints. We introduce MIRNet (Medical Image Reasoner Network), a novel framework that integrates self-supervised pre-training with constrained graph-based reasoning. Tongue image diagnosis is a particularly challenging domain that requires fine-grained visual and semantic understanding. Our approach leverages self-supervised masked autoencoder (MAE) to learn transferable visual representations from unlabeled data; employs graph attention networks (GAT) to model label correlations through expert-defined structured graphs; enforces clinical priors via constraint-aware optimization using KL divergence and regularization losses; and mitigates imbalance using asymmetric loss (ASL) and boosting ensembles. To address annotation scarcity, we also introduce TongueAtlas-4K, a comprehensive expert-curated benchmark comprising 4,000 images annotated with 22 diagnostic labels--representing the largest public dataset in tongue analysis. Validation shows our method achieves state-of-the-art performance. While optimized for tongue diagnosis, the framework readily generalizes to broader diagnostic medical imaging tasks.
title MIRNet: Integrating Constrained Graph-Based Reasoning with Pre-training for Diagnostic Medical Imaging
topic Computer Vision and Pattern Recognition
Artificial Intelligence
68T07
url https://arxiv.org/abs/2511.10013