CURENet: Combining Unified Representations for Efficient Chronic Disease Prediction

Fuente: arXiv
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Main Authors: Dao, Cong-Tinh, Phan, Nguyen Minh Thao, Ding, Jun-En, Wu, Chenwei, Restrepo, David, Luo, Dongsheng, Zhao, Fanyi, Liao, Chun-Chieh, Peng, Wen-Chih, Wang, Chi-Te, Chen, Pei-Fu, Chen, Ling, Ju, Xinglong, Liu, Feng, Hung, Fang-Ming
Format: Preprint
Published: 2025
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author Dao, Cong-Tinh
Phan, Nguyen Minh Thao
Ding, Jun-En
Wu, Chenwei
Restrepo, David
Luo, Dongsheng
Zhao, Fanyi
Liao, Chun-Chieh
Peng, Wen-Chih
Wang, Chi-Te
Chen, Pei-Fu
Chen, Ling
Ju, Xinglong
Liu, Feng
Hung, Fang-Ming
author_facet Dao, Cong-Tinh
Phan, Nguyen Minh Thao
Ding, Jun-En
Wu, Chenwei
Restrepo, David
Luo, Dongsheng
Zhao, Fanyi
Liao, Chun-Chieh
Peng, Wen-Chih
Wang, Chi-Te
Chen, Pei-Fu
Chen, Ling
Ju, Xinglong
Liu, Feng
Hung, Fang-Ming
contents Electronic health records (EHRs) are designed to synthesize diverse data types, including unstructured clinical notes, structured lab tests, and time-series visit data. Physicians draw on these multimodal and temporal sources of EHR data to form a comprehensive view of a patient's health, which is crucial for informed therapeutic decision-making. Yet, most predictive models fail to fully capture the interactions, redundancies, and temporal patterns across multiple data modalities, often focusing on a single data type or overlooking these complexities. In this paper, we present CURENet, a multimodal model (Combining Unified Representations for Efficient chronic disease prediction) that integrates unstructured clinical notes, lab tests, and patients' time-series data by utilizing large language models (LLMs) for clinical text processing and textual lab tests, as well as transformer encoders for longitudinal sequential visits. CURENet has been capable of capturing the intricate interaction between different forms of clinical data and creating a more reliable predictive model for chronic illnesses. We evaluated CURENet using the public MIMIC-III and private FEMH datasets, where it achieved over 94\% accuracy in predicting the top 10 chronic conditions in a multi-label framework. Our findings highlight the potential of multimodal EHR integration to enhance clinical decision-making and improve patient outcomes.
format Preprint
id arxiv_https___arxiv_org_abs_2511_11423
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle CURENet: Combining Unified Representations for Efficient Chronic Disease Prediction
Dao, Cong-Tinh
Phan, Nguyen Minh Thao
Ding, Jun-En
Wu, Chenwei
Restrepo, David
Luo, Dongsheng
Zhao, Fanyi
Liao, Chun-Chieh
Peng, Wen-Chih
Wang, Chi-Te
Chen, Pei-Fu
Chen, Ling
Ju, Xinglong
Liu, Feng
Hung, Fang-Ming
Artificial Intelligence
Electronic health records (EHRs) are designed to synthesize diverse data types, including unstructured clinical notes, structured lab tests, and time-series visit data. Physicians draw on these multimodal and temporal sources of EHR data to form a comprehensive view of a patient's health, which is crucial for informed therapeutic decision-making. Yet, most predictive models fail to fully capture the interactions, redundancies, and temporal patterns across multiple data modalities, often focusing on a single data type or overlooking these complexities. In this paper, we present CURENet, a multimodal model (Combining Unified Representations for Efficient chronic disease prediction) that integrates unstructured clinical notes, lab tests, and patients' time-series data by utilizing large language models (LLMs) for clinical text processing and textual lab tests, as well as transformer encoders for longitudinal sequential visits. CURENet has been capable of capturing the intricate interaction between different forms of clinical data and creating a more reliable predictive model for chronic illnesses. We evaluated CURENet using the public MIMIC-III and private FEMH datasets, where it achieved over 94\% accuracy in predicting the top 10 chronic conditions in a multi-label framework. Our findings highlight the potential of multimodal EHR integration to enhance clinical decision-making and improve patient outcomes.
title CURENet: Combining Unified Representations for Efficient Chronic Disease Prediction
topic Artificial Intelligence
url https://arxiv.org/abs/2511.11423