Data-Driven Design Rules for TADF Emitters from a High-Throughput Screening of 747 Molecules

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Main Authors: Njafa, Jean-Pierre Tchapet, Tcheuffa, Elvira Vanelle Kameni, Foumkpou, Aissatou Maghame, Engo, Serge Guy Nana
Format: Preprint
Published: 2025
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author Njafa, Jean-Pierre Tchapet
Tcheuffa, Elvira Vanelle Kameni
Foumkpou, Aissatou Maghame
Engo, Serge Guy Nana
author_facet Njafa, Jean-Pierre Tchapet
Tcheuffa, Elvira Vanelle Kameni
Foumkpou, Aissatou Maghame
Engo, Serge Guy Nana
contents TADF emitter performance depends on both thermodynamic and kinetic factors. We analyze 747 experimentally known TADF molecules computationally to extract quantitative design guidelines. Using a validated xTB-based workflow, we examine how architecture, geometry, and electronic structure affect photophysical properties. Among architectures, D-A-D frameworks achieve the smallest \deltaest. A favorable torsional angle of $50°-90°$ balances small $ΔE_{\text{ST}}$ with the spin--orbit coupling needed for reverse intersystem crossing. Clustering separates high-performance candidates and highlights multi-resonance emitters for blue emission. From these results, we identify 127 candidates with predicted $ΔE_{\text{ST}} < 0.1 eV$ and oscillator strength $f > 0.1$. These HTVS-derived design guidelines and candidates can guide future TADF emitter development.
format Preprint
id arxiv_https___arxiv_org_abs_2511_11606
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Data-Driven Design Rules for TADF Emitters from a High-Throughput Screening of 747 Molecules
Njafa, Jean-Pierre Tchapet
Tcheuffa, Elvira Vanelle Kameni
Foumkpou, Aissatou Maghame
Engo, Serge Guy Nana
Applied Physics
TADF emitter performance depends on both thermodynamic and kinetic factors. We analyze 747 experimentally known TADF molecules computationally to extract quantitative design guidelines. Using a validated xTB-based workflow, we examine how architecture, geometry, and electronic structure affect photophysical properties. Among architectures, D-A-D frameworks achieve the smallest \deltaest. A favorable torsional angle of $50°-90°$ balances small $ΔE_{\text{ST}}$ with the spin--orbit coupling needed for reverse intersystem crossing. Clustering separates high-performance candidates and highlights multi-resonance emitters for blue emission. From these results, we identify 127 candidates with predicted $ΔE_{\text{ST}} < 0.1 eV$ and oscillator strength $f > 0.1$. These HTVS-derived design guidelines and candidates can guide future TADF emitter development.
title Data-Driven Design Rules for TADF Emitters from a High-Throughput Screening of 747 Molecules
topic Applied Physics
url https://arxiv.org/abs/2511.11606