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Auteurs principaux: Liu, Chi, Liu, Jincheng, Zhu, Congcong, Wang, Minghao, Shen, Sheng, Gu, Jia, Zhu, Tianqing, Zhou, Wanlei
Format: Preprint
Publié: 2025
Sujets:
Accès en ligne:https://arxiv.org/abs/2511.12301
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author Liu, Chi
Liu, Jincheng
Zhu, Congcong
Wang, Minghao
Shen, Sheng
Gu, Jia
Zhu, Tianqing
Zhou, Wanlei
author_facet Liu, Chi
Liu, Jincheng
Zhu, Congcong
Wang, Minghao
Shen, Sheng
Gu, Jia
Zhu, Tianqing
Zhou, Wanlei
contents Developing Medical AI relies on large datasets and easily suffers from data scarcity. Generative data augmentation (GDA) using AI generative models offers a solution to synthesize realistic medical images. However, the bias in GDA is often underestimated in medical domains, with concerns about the risk of introducing detrimental features generated by AI and harming downstream tasks. This paper identifies the frequency misalignment between real and synthesized images as one of the key factors underlying unreliable GDA and proposes the Frequency Recalibration (FreRec) method to reduce the frequency distributional discrepancy and thus improve GDA. FreRec involves (1) Statistical High-frequency Replacement (SHR) to roughly align high-frequency components and (2) Reconstructive High-frequency Mapping (RHM) to enhance image quality and reconstruct high-frequency details. Extensive experiments were conducted in various medical datasets, including brain MRIs, chest X-rays, and fundus images. The results show that FreRec significantly improves downstream medical image classification performance compared to uncalibrated AI-synthesized samples. FreRec is a standalone post-processing step that is compatible with any generative model and can integrate seamlessly with common medical GDA pipelines.
format Preprint
id arxiv_https___arxiv_org_abs_2511_12301
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Rethinking Bias in Generative Data Augmentation for Medical AI: a Frequency Recalibration Method
Liu, Chi
Liu, Jincheng
Zhu, Congcong
Wang, Minghao
Shen, Sheng
Gu, Jia
Zhu, Tianqing
Zhou, Wanlei
Computer Vision and Pattern Recognition
Artificial Intelligence
Developing Medical AI relies on large datasets and easily suffers from data scarcity. Generative data augmentation (GDA) using AI generative models offers a solution to synthesize realistic medical images. However, the bias in GDA is often underestimated in medical domains, with concerns about the risk of introducing detrimental features generated by AI and harming downstream tasks. This paper identifies the frequency misalignment between real and synthesized images as one of the key factors underlying unreliable GDA and proposes the Frequency Recalibration (FreRec) method to reduce the frequency distributional discrepancy and thus improve GDA. FreRec involves (1) Statistical High-frequency Replacement (SHR) to roughly align high-frequency components and (2) Reconstructive High-frequency Mapping (RHM) to enhance image quality and reconstruct high-frequency details. Extensive experiments were conducted in various medical datasets, including brain MRIs, chest X-rays, and fundus images. The results show that FreRec significantly improves downstream medical image classification performance compared to uncalibrated AI-synthesized samples. FreRec is a standalone post-processing step that is compatible with any generative model and can integrate seamlessly with common medical GDA pipelines.
title Rethinking Bias in Generative Data Augmentation for Medical AI: a Frequency Recalibration Method
topic Computer Vision and Pattern Recognition
Artificial Intelligence
url https://arxiv.org/abs/2511.12301