CODE-II: A large-scale dataset for artificial intelligence in ECG analysis

Fuente: arXiv
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Auteurs principaux: Abreu, Petrus E. O. G. B., Paixão, Gabriela M. M., Li, Jiawei, Gomes, Paulo R., Macfarlane, Peter W., Oliveira, Ana C. S., Carvalho, Vinicius T., Schön, Thomas B., Ribeiro, Antonio Luiz P., Ribeiro, Antônio H.
Format: Preprint
Publié: 2025
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author Abreu, Petrus E. O. G. B.
Paixão, Gabriela M. M.
Li, Jiawei
Gomes, Paulo R.
Macfarlane, Peter W.
Oliveira, Ana C. S.
Carvalho, Vinicius T.
Schön, Thomas B.
Ribeiro, Antonio Luiz P.
Ribeiro, Antônio H.
author_facet Abreu, Petrus E. O. G. B.
Paixão, Gabriela M. M.
Li, Jiawei
Gomes, Paulo R.
Macfarlane, Peter W.
Oliveira, Ana C. S.
Carvalho, Vinicius T.
Schön, Thomas B.
Ribeiro, Antonio Luiz P.
Ribeiro, Antônio H.
contents Data-driven methods for electrocardiogram (ECG) interpretation are rapidly progressing. Large datasets have enabled advances in artificial intelligence (AI) based ECG analysis, yet limitations in annotation quality, size, and scope remain major challenges. Here we present CODE-II, a large-scale real-world dataset of 2,735,269 12-lead ECGs from 2,093,807 adult patients collected by the Telehealth Network of Minas Gerais (TNMG), Brazil. Each exam was annotated using standardized diagnostic criteria and reviewed by cardiologists. A defining feature of CODE-II is a set of 66 clinically meaningful diagnostic classes, developed with cardiologist input and routinely used in telehealth practice. We additionally provide an open available subset: CODE-II-open, a public subset of 15,000 patients, and the CODE-II-test, a non-overlapping set of 8,475 exams reviewed by multiple cardiologists for blinded evaluation. A neural network pre-trained on CODE-II achieved superior transfer performance on external benchmarks (PTB-XL and CPSC 2018) and outperformed alternatives trained on larger datasets.
format Preprint
id arxiv_https___arxiv_org_abs_2511_15632
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle CODE-II: A large-scale dataset for artificial intelligence in ECG analysis
Abreu, Petrus E. O. G. B.
Paixão, Gabriela M. M.
Li, Jiawei
Gomes, Paulo R.
Macfarlane, Peter W.
Oliveira, Ana C. S.
Carvalho, Vinicius T.
Schön, Thomas B.
Ribeiro, Antonio Luiz P.
Ribeiro, Antônio H.
Signal Processing
Machine Learning
Data-driven methods for electrocardiogram (ECG) interpretation are rapidly progressing. Large datasets have enabled advances in artificial intelligence (AI) based ECG analysis, yet limitations in annotation quality, size, and scope remain major challenges. Here we present CODE-II, a large-scale real-world dataset of 2,735,269 12-lead ECGs from 2,093,807 adult patients collected by the Telehealth Network of Minas Gerais (TNMG), Brazil. Each exam was annotated using standardized diagnostic criteria and reviewed by cardiologists. A defining feature of CODE-II is a set of 66 clinically meaningful diagnostic classes, developed with cardiologist input and routinely used in telehealth practice. We additionally provide an open available subset: CODE-II-open, a public subset of 15,000 patients, and the CODE-II-test, a non-overlapping set of 8,475 exams reviewed by multiple cardiologists for blinded evaluation. A neural network pre-trained on CODE-II achieved superior transfer performance on external benchmarks (PTB-XL and CPSC 2018) and outperformed alternatives trained on larger datasets.
title CODE-II: A large-scale dataset for artificial intelligence in ECG analysis
topic Signal Processing
Machine Learning
url https://arxiv.org/abs/2511.15632