Sparse Mixture-of-Experts for Multi-Channel Imaging: Are All Channel Interactions Required?

Fuente: arXiv
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Autori principali: Yun, Sukwon, Yao, Heming, Hoeckendorf, Burkhard, Richmond, David, Regev, Aviv, Littman, Russell
Natura: Preprint
Pubblicazione: 2025
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author Yun, Sukwon
Yao, Heming
Hoeckendorf, Burkhard
Richmond, David
Regev, Aviv
Littman, Russell
author_facet Yun, Sukwon
Yao, Heming
Hoeckendorf, Burkhard
Richmond, David
Regev, Aviv
Littman, Russell
contents Vision Transformers ($\text{ViTs}$) have become the backbone of vision foundation models, yet their optimization for multi-channel domains - such as cell painting or satellite imagery - remains underexplored. A key challenge in these domains is capturing interactions between channels, as each channel carries different information. While existing works have shown efficacy by treating each channel independently during tokenization, this approach naturally introduces a major computational bottleneck in the attention block - channel-wise comparisons leads to a quadratic growth in attention, resulting in excessive $\text{FLOPs}$ and high training cost. In this work, we shift focus from efficacy to the overlooked efficiency challenge in cross-channel attention and ask: "Is it necessary to model all channel interactions?". Inspired by the philosophy of Sparse Mixture-of-Experts ($\text{MoE}$), we propose MoE-ViT, a Mixture-of-Experts architecture for multi-channel images in $\text{ViTs}$, which treats each channel as an expert and employs a lightweight router to select only the most relevant experts per patch for attention. Proof-of-concept experiments on real-world datasets - JUMP-CP and So2Sat - demonstrate that $\text{MoE-ViT}$ achieves substantial efficiency gains without sacrificing, and in some cases enhancing, performance, making it a practical and attractive backbone for multi-channel imaging.
format Preprint
id arxiv_https___arxiv_org_abs_2511_17400
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Sparse Mixture-of-Experts for Multi-Channel Imaging: Are All Channel Interactions Required?
Yun, Sukwon
Yao, Heming
Hoeckendorf, Burkhard
Richmond, David
Regev, Aviv
Littman, Russell
Computer Vision and Pattern Recognition
Artificial Intelligence
Vision Transformers ($\text{ViTs}$) have become the backbone of vision foundation models, yet their optimization for multi-channel domains - such as cell painting or satellite imagery - remains underexplored. A key challenge in these domains is capturing interactions between channels, as each channel carries different information. While existing works have shown efficacy by treating each channel independently during tokenization, this approach naturally introduces a major computational bottleneck in the attention block - channel-wise comparisons leads to a quadratic growth in attention, resulting in excessive $\text{FLOPs}$ and high training cost. In this work, we shift focus from efficacy to the overlooked efficiency challenge in cross-channel attention and ask: "Is it necessary to model all channel interactions?". Inspired by the philosophy of Sparse Mixture-of-Experts ($\text{MoE}$), we propose MoE-ViT, a Mixture-of-Experts architecture for multi-channel images in $\text{ViTs}$, which treats each channel as an expert and employs a lightweight router to select only the most relevant experts per patch for attention. Proof-of-concept experiments on real-world datasets - JUMP-CP and So2Sat - demonstrate that $\text{MoE-ViT}$ achieves substantial efficiency gains without sacrificing, and in some cases enhancing, performance, making it a practical and attractive backbone for multi-channel imaging.
title Sparse Mixture-of-Experts for Multi-Channel Imaging: Are All Channel Interactions Required?
topic Computer Vision and Pattern Recognition
Artificial Intelligence
url https://arxiv.org/abs/2511.17400