Block Length Gain for Nanopore Channels

Fuente: arXiv
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Hauptverfasser: Lin, Yu-Ting, Wang, Hsin-Po, Guruswami, Venkatesan
Format: Preprint
Veröffentlicht: 2025
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author Lin, Yu-Ting
Wang, Hsin-Po
Guruswami, Venkatesan
author_facet Lin, Yu-Ting
Wang, Hsin-Po
Guruswami, Venkatesan
contents DNA is an attractive candidate for data storage. Its millennial durability and nanometer scale offer exceptional data density and longevity. Its relevance to medical applications also drives advances in DNA-related biotechnology. To protect our data against errors, a straightforward approach uses one error-correcting code per DNA strand, with a Reed--Solomon code protecting the collection of strands. A downside is that current technology can only synthesize strands 200--300 nucleotides long. At this block length, the inner code rate suffers a significant finite-length penalty, making its effective capacity hard to characterize. Last year, we proposed $\textit{Geno-Weaving}$ in a JSAIT publication. The idea is to protect the same position across multiple strands using one code; this provably achieves capacity against substitution errors. In this paper, we extend the idea to combat deletion errors and show two more advantages of Geno-Weaving: (1) Because the number of strands is 3--4 orders of magnitude larger than the strand length, the finite-length penalty vanishes. (2) At realistic deletion rates $0.1\%$--$10\%$, Geno-Weaving designed for BSCs works well empirically, bypassing the need to tailor the design for deletion channels.
format Preprint
id arxiv_https___arxiv_org_abs_2511_18027
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Block Length Gain for Nanopore Channels
Lin, Yu-Ting
Wang, Hsin-Po
Guruswami, Venkatesan
Information Theory
DNA is an attractive candidate for data storage. Its millennial durability and nanometer scale offer exceptional data density and longevity. Its relevance to medical applications also drives advances in DNA-related biotechnology. To protect our data against errors, a straightforward approach uses one error-correcting code per DNA strand, with a Reed--Solomon code protecting the collection of strands. A downside is that current technology can only synthesize strands 200--300 nucleotides long. At this block length, the inner code rate suffers a significant finite-length penalty, making its effective capacity hard to characterize. Last year, we proposed $\textit{Geno-Weaving}$ in a JSAIT publication. The idea is to protect the same position across multiple strands using one code; this provably achieves capacity against substitution errors. In this paper, we extend the idea to combat deletion errors and show two more advantages of Geno-Weaving: (1) Because the number of strands is 3--4 orders of magnitude larger than the strand length, the finite-length penalty vanishes. (2) At realistic deletion rates $0.1\%$--$10\%$, Geno-Weaving designed for BSCs works well empirically, bypassing the need to tailor the design for deletion channels.
title Block Length Gain for Nanopore Channels
topic Information Theory
url https://arxiv.org/abs/2511.18027