Topology Controls the Phase Separation Dynamics of Multicomponent Fluid Mixtures

Fuente: arXiv
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Autores principales: Rennick, Michael, Zhang, Xitong, Kusumaatmaja, Halim
Formato: Preprint
Publicado: 2025
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author Rennick, Michael
Zhang, Xitong
Kusumaatmaja, Halim
author_facet Rennick, Michael
Zhang, Xitong
Kusumaatmaja, Halim
contents Fluid mixtures, such as the cellular cytoplasm and synthetic DNA nanostars, can spontaneously compartmentalize into many coexisting phases through liquid-liquid phase separation. Despite the diversity of fluid structures that emerge from interactions between different phases, the physical principles governing their spatiotemporal organization remain unclear. In this work, we show that the dynamics of multicomponent phase separation are intimately connected to mathematical coloring problems, including the four-color theorem. By confining the system to thin geometries, we demonstrate that the four-color theorem permits arrangements of fluid compartments that lead to suppressed coalescence. As a consequence, hydrodynamics is arrested, and the diffusion-dominated coarsening dynamics can be collapsed to a universal master curve. Varying the fluid interfacial tensions can change which arrangements are energetically permissible, resulting in highly complex coarsening dynamics that differ for each phase. In unconfined three-dimensional systems, the absence of an equivalent to the four-color theorem means that suppression of coalescence is only reached asymptotically for large numbers of phases, rather than at a sharp threshold. In general, the coloring approach employed here offers a topological framework for understanding the dynamic behaviour of phase separating fluid mixtures.
format Preprint
id arxiv_https___arxiv_org_abs_2511_20215
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Topology Controls the Phase Separation Dynamics of Multicomponent Fluid Mixtures
Rennick, Michael
Zhang, Xitong
Kusumaatmaja, Halim
Fluid Dynamics
Fluid mixtures, such as the cellular cytoplasm and synthetic DNA nanostars, can spontaneously compartmentalize into many coexisting phases through liquid-liquid phase separation. Despite the diversity of fluid structures that emerge from interactions between different phases, the physical principles governing their spatiotemporal organization remain unclear. In this work, we show that the dynamics of multicomponent phase separation are intimately connected to mathematical coloring problems, including the four-color theorem. By confining the system to thin geometries, we demonstrate that the four-color theorem permits arrangements of fluid compartments that lead to suppressed coalescence. As a consequence, hydrodynamics is arrested, and the diffusion-dominated coarsening dynamics can be collapsed to a universal master curve. Varying the fluid interfacial tensions can change which arrangements are energetically permissible, resulting in highly complex coarsening dynamics that differ for each phase. In unconfined three-dimensional systems, the absence of an equivalent to the four-color theorem means that suppression of coalescence is only reached asymptotically for large numbers of phases, rather than at a sharp threshold. In general, the coloring approach employed here offers a topological framework for understanding the dynamic behaviour of phase separating fluid mixtures.
title Topology Controls the Phase Separation Dynamics of Multicomponent Fluid Mixtures
topic Fluid Dynamics
url https://arxiv.org/abs/2511.20215