Automated Statistical and Machine Learning Platform for Biological Research

Fuente: arXiv
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Auteurs principaux: Lego, Luke Rimmo, Gauthier, Samantha, Baptiste, Denver Jn.
Format: Preprint
Publié: 2025
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author Lego, Luke Rimmo
Gauthier, Samantha
Baptiste, Denver Jn.
author_facet Lego, Luke Rimmo
Gauthier, Samantha
Baptiste, Denver Jn.
contents Research increasingly relies on computational methods to analyze experimental data and predict molecular properties. Current approaches often require researchers to use a variety of tools for statistical analysis and machine learning, creating workflow inefficiencies. We present an integrated platform that combines classical statistical methods with Random Forest classification for comprehensive data analysis that can be used in the biological sciences. The platform implements automated hyperparameter optimization, feature importance analysis, and a suite of statistical tests including t tests, ANOVA, and Pearson correlation analysis. Our methodology addresses the gap between traditional statistical software, modern machine learning frameworks and biology, by providing a unified interface accessible to researchers without extensive programming experience. The system achieves this through automatic data preprocessing, categorical encoding, and adaptive model configuration based on dataset characteristics. Initial testing protocols are designed to evaluate classification accuracy across diverse chemical datasets with varying feature distributions. This work demonstrates that integrating statistical rigor with machine learning interpretability can accelerate biological discovery workflows while maintaining methodological soundness. The platform's modular architecture enables future extensions to additional machine learning algorithms and statistical procedures relevant to bioinformatics.
format Preprint
id arxiv_https___arxiv_org_abs_2511_21770
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Automated Statistical and Machine Learning Platform for Biological Research
Lego, Luke Rimmo
Gauthier, Samantha
Baptiste, Denver Jn.
Quantitative Methods
Machine Learning
Research increasingly relies on computational methods to analyze experimental data and predict molecular properties. Current approaches often require researchers to use a variety of tools for statistical analysis and machine learning, creating workflow inefficiencies. We present an integrated platform that combines classical statistical methods with Random Forest classification for comprehensive data analysis that can be used in the biological sciences. The platform implements automated hyperparameter optimization, feature importance analysis, and a suite of statistical tests including t tests, ANOVA, and Pearson correlation analysis. Our methodology addresses the gap between traditional statistical software, modern machine learning frameworks and biology, by providing a unified interface accessible to researchers without extensive programming experience. The system achieves this through automatic data preprocessing, categorical encoding, and adaptive model configuration based on dataset characteristics. Initial testing protocols are designed to evaluate classification accuracy across diverse chemical datasets with varying feature distributions. This work demonstrates that integrating statistical rigor with machine learning interpretability can accelerate biological discovery workflows while maintaining methodological soundness. The platform's modular architecture enables future extensions to additional machine learning algorithms and statistical procedures relevant to bioinformatics.
title Automated Statistical and Machine Learning Platform for Biological Research
topic Quantitative Methods
Machine Learning
url https://arxiv.org/abs/2511.21770