Overall marginalized models for longitudinal zero-inflated count data

Fuente: arXiv
Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Lee, Keunbaik, Jang, Eun Jin, Dey, Dipak
Format: Preprint
Veröffentlicht: 2025
Schlagworte:
Online-Zugang:
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
_version_ 1866915641971179520
author Lee, Keunbaik
Jang, Eun Jin
Dey, Dipak
author_facet Lee, Keunbaik
Jang, Eun Jin
Dey, Dipak
contents To analyze longitudinal zero-inflated count data, we extend existing models by introducing marginalized zero-inflated Poisson (MZIP) models with random effects, which explicitly capture the marginal effect of covariates and address limitations of previous methods. These models provide a clearer interpretation of the overall mean effect of covariates on zero-inflated count data. To further accommodate overdispersion, we develop marginalized zero-inflated negative binomial (MZINB) models. Both models incorporate subject-specific heterogeneity through a flexible random effects covariance structure. Simulation studies are conducted to evaluate the performance of the MZIP and MZINB models, comparing their inference under both homogeneous and heterogeneous random effects. Finally, we illustrate the applicability of the proposed models through an analysis of systemic lupus erythematosus data.
format Preprint
id arxiv_https___arxiv_org_abs_2511_22223
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Overall marginalized models for longitudinal zero-inflated count data
Lee, Keunbaik
Jang, Eun Jin
Dey, Dipak
Methodology
To analyze longitudinal zero-inflated count data, we extend existing models by introducing marginalized zero-inflated Poisson (MZIP) models with random effects, which explicitly capture the marginal effect of covariates and address limitations of previous methods. These models provide a clearer interpretation of the overall mean effect of covariates on zero-inflated count data. To further accommodate overdispersion, we develop marginalized zero-inflated negative binomial (MZINB) models. Both models incorporate subject-specific heterogeneity through a flexible random effects covariance structure. Simulation studies are conducted to evaluate the performance of the MZIP and MZINB models, comparing their inference under both homogeneous and heterogeneous random effects. Finally, we illustrate the applicability of the proposed models through an analysis of systemic lupus erythematosus data.
title Overall marginalized models for longitudinal zero-inflated count data
topic Methodology
url https://arxiv.org/abs/2511.22223