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Main Authors: Cao, Qinyi, Fan, Jianan, Cai, Weidong
Format: Preprint
Published: 2025
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Online Access:https://arxiv.org/abs/2512.00310
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author Cao, Qinyi
Fan, Jianan
Cai, Weidong
author_facet Cao, Qinyi
Fan, Jianan
Cai, Weidong
contents Unsupervised anomaly detection aims to identify anomalies without pixel-level annotations. Synthetic anomaly-based methods exhibit a unique capacity to introduce controllable irregularities with known masks, enabling explicit supervision during training. However, existing methods often produce synthetic anomalies that are visually distinct from real pathological patterns and ignore anatomical structure. This paper presents a novel Anatomy-aware Realistic Texture-based Anomaly Synthesis framework (ART-ASyn) for chest X-rays that generates realistic and anatomically consistent lung opacity related anomalies using texture-based augmentation guided by our proposed Progressive Binary Thresholding Segmentation method (PBTSeg) for lung segmentation. The generated paired samples of synthetic anomalies and their corresponding precise pixel-level anomaly mask for each normal sample enable explicit segmentation supervision. In contrast to prior work limited to one-class classification, ART-ASyn is further evaluated for zero-shot anomaly segmentation, demonstrating generalizability on an unseen dataset without target-domain annotations. Code availability is available at https://github.com/angelacao-hub/ART-ASyn.
format Preprint
id arxiv_https___arxiv_org_abs_2512_00310
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle ART-ASyn: Anatomy-aware Realistic Texture-based Anomaly Synthesis Framework for Chest X-Rays
Cao, Qinyi
Fan, Jianan
Cai, Weidong
Computer Vision and Pattern Recognition
Unsupervised anomaly detection aims to identify anomalies without pixel-level annotations. Synthetic anomaly-based methods exhibit a unique capacity to introduce controllable irregularities with known masks, enabling explicit supervision during training. However, existing methods often produce synthetic anomalies that are visually distinct from real pathological patterns and ignore anatomical structure. This paper presents a novel Anatomy-aware Realistic Texture-based Anomaly Synthesis framework (ART-ASyn) for chest X-rays that generates realistic and anatomically consistent lung opacity related anomalies using texture-based augmentation guided by our proposed Progressive Binary Thresholding Segmentation method (PBTSeg) for lung segmentation. The generated paired samples of synthetic anomalies and their corresponding precise pixel-level anomaly mask for each normal sample enable explicit segmentation supervision. In contrast to prior work limited to one-class classification, ART-ASyn is further evaluated for zero-shot anomaly segmentation, demonstrating generalizability on an unseen dataset without target-domain annotations. Code availability is available at https://github.com/angelacao-hub/ART-ASyn.
title ART-ASyn: Anatomy-aware Realistic Texture-based Anomaly Synthesis Framework for Chest X-Rays
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2512.00310