Subgroup Validity in Machine Learning for Echocardiogram Data

Fuente: arXiv
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Autores principales: Feeney, Cynthia, Williams, Shane, Wessler, Benjamin S., Hughes, Michael C.
Formato: Preprint
Publicado: 2025
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author Feeney, Cynthia
Williams, Shane
Wessler, Benjamin S.
Hughes, Michael C.
author_facet Feeney, Cynthia
Williams, Shane
Wessler, Benjamin S.
Hughes, Michael C.
contents Echocardiogram datasets enable training deep learning models to automate interpretation of cardiac ultrasound, thereby expanding access to accurate readings of diagnostically-useful images. However, the gender, sex, race, and ethnicity of the patients in these datasets are underreported and subgroup-specific predictive performance is unevaluated. These reporting deficiencies raise concerns about subgroup validity that must be studied and addressed before model deployment. In this paper, we show that current open echocardiogram datasets are unable to assuage subgroup validity concerns. We improve sociodemographic reporting for two datasets: TMED-2 and MIMIC-IV-ECHO. Analysis of six open datasets reveals no consideration of gender-diverse patients and insufficient patient counts for many racial and ethnic groups. We further perform an exploratory subgroup analysis of two published aortic stenosis detection models on TMED-2. We find insufficient evidence for subgroup validity for sex, racial, and ethnic subgroups. Our findings highlight that more data for underrepresented subgroups, improved demographic reporting, and subgroup-focused analyses are needed to prove subgroup validity in future work.
format Preprint
id arxiv_https___arxiv_org_abs_2512_00976
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Subgroup Validity in Machine Learning for Echocardiogram Data
Feeney, Cynthia
Williams, Shane
Wessler, Benjamin S.
Hughes, Michael C.
Machine Learning
Other Statistics
Echocardiogram datasets enable training deep learning models to automate interpretation of cardiac ultrasound, thereby expanding access to accurate readings of diagnostically-useful images. However, the gender, sex, race, and ethnicity of the patients in these datasets are underreported and subgroup-specific predictive performance is unevaluated. These reporting deficiencies raise concerns about subgroup validity that must be studied and addressed before model deployment. In this paper, we show that current open echocardiogram datasets are unable to assuage subgroup validity concerns. We improve sociodemographic reporting for two datasets: TMED-2 and MIMIC-IV-ECHO. Analysis of six open datasets reveals no consideration of gender-diverse patients and insufficient patient counts for many racial and ethnic groups. We further perform an exploratory subgroup analysis of two published aortic stenosis detection models on TMED-2. We find insufficient evidence for subgroup validity for sex, racial, and ethnic subgroups. Our findings highlight that more data for underrepresented subgroups, improved demographic reporting, and subgroup-focused analyses are needed to prove subgroup validity in future work.
title Subgroup Validity in Machine Learning for Echocardiogram Data
topic Machine Learning
Other Statistics
url https://arxiv.org/abs/2512.00976