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Main Authors: Li, Xin, Zhu, Wenhui, Dong, Xuanzhao, Wang, Hao, Xiong, Yujian, Dumitrascu, Oana, Wang, Yalin
Format: Preprint
Published: 2025
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Online Access:https://arxiv.org/abs/2512.01273
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author Li, Xin
Zhu, Wenhui
Dong, Xuanzhao
Wang, Hao
Xiong, Yujian
Dumitrascu, Oana
Wang, Yalin
author_facet Li, Xin
Zhu, Wenhui
Dong, Xuanzhao
Wang, Hao
Xiong, Yujian
Dumitrascu, Oana
Wang, Yalin
contents Retinal imaging is a critical, non-invasive modality for the early detection and monitoring of ocular and systemic diseases. Deep learning, particularly convolutional neural networks (CNNs), has significant progress in automated retinal analysis, supporting tasks such as fundus image classification, lesion detection, and vessel segmentation. As a representative lightweight network, nnMobileNet has demonstrated strong performance across multiple retinal benchmarks while remaining computationally efficient. However, purely convolutional architectures inherently struggle to capture long-range dependencies and model the irregular lesions and elongated vascular patterns that characterize on retinal images, despite the critical importance of vascular features for reliable clinical diagnosis. To further advance this line of work and extend the original vision of nnMobileNet, we propose nnMobileNet++, a hybrid architecture that progressively bridges convolutional and transformer representations. The framework integrates three key components: (i) dynamic snake convolution for boundary-aware feature extraction, (ii) stage-specific transformer blocks introduced after the second down-sampling stage for global context modeling, and (iii) retinal image pretraining to improve generalization. Experiments on multiple public retinal datasets for classification, together with ablation studies, demonstrate that nnMobileNet++ achieves state-of-the-art or highly competitive accuracy while maintaining low computational cost, underscoring its potential as a lightweight yet effective framework for retinal image analysis.
format Preprint
id arxiv_https___arxiv_org_abs_2512_01273
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle nnMobileNet++: Towards Efficient Hybrid Networks for Retinal Image Analysis
Li, Xin
Zhu, Wenhui
Dong, Xuanzhao
Wang, Hao
Xiong, Yujian
Dumitrascu, Oana
Wang, Yalin
Computer Vision and Pattern Recognition
Retinal imaging is a critical, non-invasive modality for the early detection and monitoring of ocular and systemic diseases. Deep learning, particularly convolutional neural networks (CNNs), has significant progress in automated retinal analysis, supporting tasks such as fundus image classification, lesion detection, and vessel segmentation. As a representative lightweight network, nnMobileNet has demonstrated strong performance across multiple retinal benchmarks while remaining computationally efficient. However, purely convolutional architectures inherently struggle to capture long-range dependencies and model the irregular lesions and elongated vascular patterns that characterize on retinal images, despite the critical importance of vascular features for reliable clinical diagnosis. To further advance this line of work and extend the original vision of nnMobileNet, we propose nnMobileNet++, a hybrid architecture that progressively bridges convolutional and transformer representations. The framework integrates three key components: (i) dynamic snake convolution for boundary-aware feature extraction, (ii) stage-specific transformer blocks introduced after the second down-sampling stage for global context modeling, and (iii) retinal image pretraining to improve generalization. Experiments on multiple public retinal datasets for classification, together with ablation studies, demonstrate that nnMobileNet++ achieves state-of-the-art or highly competitive accuracy while maintaining low computational cost, underscoring its potential as a lightweight yet effective framework for retinal image analysis.
title nnMobileNet++: Towards Efficient Hybrid Networks for Retinal Image Analysis
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2512.01273