Optimizing Stroke Risk Prediction: A Machine Learning Pipeline Combining ROS-Balanced Ensembles and XAI

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Hauptverfasser: Akib, A S M Ahsanul Sarkar, Khawla, Raduana, Hasib, Abdul
Format: Preprint
Veröffentlicht: 2025
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author Akib, A S M Ahsanul Sarkar
Khawla, Raduana
Hasib, Abdul
author_facet Akib, A S M Ahsanul Sarkar
Khawla, Raduana
Hasib, Abdul
contents Stroke is a major cause of death and permanent impairment, making it a major worldwide health concern. For prompt intervention and successful preventative tactics, early risk assessment is essential. To address this challenge, we used ensemble modeling and explainable AI (XAI) techniques to create an interpretable machine learning framework for stroke risk prediction. A thorough evaluation of 10 different machine learning models using 5-fold cross-validation across several datasets was part of our all-inclusive strategy, which also included feature engineering and data pretreatment (using Random Over-Sampling (ROS) to solve class imbalance). Our optimized ensemble model (Random Forest + ExtraTrees + XGBoost) performed exceptionally well, obtaining a strong 99.09% accuracy on the Stroke Prediction Dataset (SPD). We improved the model's transparency and clinical applicability by identifying three important clinical variables using LIME-based interpretability analysis: age, hypertension, and glucose levels. Through early prediction, this study highlights how combining ensemble learning with explainable AI (XAI) can deliver highly accurate and interpretable stroke risk assessment. By enabling data-driven prevention and personalized clinical decisions, our framework has the potential to transform stroke prediction and cardiovascular risk management.
format Preprint
id arxiv_https___arxiv_org_abs_2512_01333
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Optimizing Stroke Risk Prediction: A Machine Learning Pipeline Combining ROS-Balanced Ensembles and XAI
Akib, A S M Ahsanul Sarkar
Khawla, Raduana
Hasib, Abdul
Computer Vision and Pattern Recognition
Machine Learning
Stroke is a major cause of death and permanent impairment, making it a major worldwide health concern. For prompt intervention and successful preventative tactics, early risk assessment is essential. To address this challenge, we used ensemble modeling and explainable AI (XAI) techniques to create an interpretable machine learning framework for stroke risk prediction. A thorough evaluation of 10 different machine learning models using 5-fold cross-validation across several datasets was part of our all-inclusive strategy, which also included feature engineering and data pretreatment (using Random Over-Sampling (ROS) to solve class imbalance). Our optimized ensemble model (Random Forest + ExtraTrees + XGBoost) performed exceptionally well, obtaining a strong 99.09% accuracy on the Stroke Prediction Dataset (SPD). We improved the model's transparency and clinical applicability by identifying three important clinical variables using LIME-based interpretability analysis: age, hypertension, and glucose levels. Through early prediction, this study highlights how combining ensemble learning with explainable AI (XAI) can deliver highly accurate and interpretable stroke risk assessment. By enabling data-driven prevention and personalized clinical decisions, our framework has the potential to transform stroke prediction and cardiovascular risk management.
title Optimizing Stroke Risk Prediction: A Machine Learning Pipeline Combining ROS-Balanced Ensembles and XAI
topic Computer Vision and Pattern Recognition
Machine Learning
url https://arxiv.org/abs/2512.01333