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Main Authors: Marteau, Benoit L., Hornback, Andrew, Tan, Shaun Q., Lowson, Christian, Woloff, Jason, Wang, May D.
Format: Preprint
Published: 2025
Subjects:
Online Access:https://arxiv.org/abs/2512.03098
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author Marteau, Benoit L.
Hornback, Andrew
Tan, Shaun Q.
Lowson, Christian
Woloff, Jason
Wang, May D.
author_facet Marteau, Benoit L.
Hornback, Andrew
Tan, Shaun Q.
Lowson, Christian
Woloff, Jason
Wang, May D.
contents The rapid growth of Artificial Intelligence (AI) in healthcare has sparked interest in Trustworthy AI and AI Implementation Science, both of which are essential for accelerating clinical adoption. However, strict regulations, gaps between research and clinical settings, and challenges in evaluating AI systems continue to hinder real-world implementation. This study presents an AI implementation case study within Shriners Childrens (SC), a large multisite pediatric system, showcasing the modernization of SCs Research Data Warehouse (RDW) to OMOP CDM v5.4 within a secure Microsoft Fabric environment. We introduce a Python-based data quality assessment tool compatible with SCs infrastructure, extending OHDsi's R/Java-based Data Quality Dashboard (DQD) and integrating Trustworthy AI principles using the METRIC framework. This extension enhances data quality evaluation by addressing informative missingness, redundancy, timeliness, and distributional consistency. We also compare systematic and case-specific AI implementation strategies for Craniofacial Microsomia (CFM) using the FHIR standard. Our contributions include a real-world evaluation of AI implementations, integration of Trustworthy AI principles into data quality assessment, and insights into hybrid implementation strategies that blend systematic infrastructure with use-case-driven approaches to advance AI in healthcare.
format Preprint
id arxiv_https___arxiv_org_abs_2512_03098
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle An AI Implementation Science Study to Improve Trustworthy Data in a Large Healthcare System
Marteau, Benoit L.
Hornback, Andrew
Tan, Shaun Q.
Lowson, Christian
Woloff, Jason
Wang, May D.
Quantitative Methods
Machine Learning
I.2.1; H.2.1; J.3
The rapid growth of Artificial Intelligence (AI) in healthcare has sparked interest in Trustworthy AI and AI Implementation Science, both of which are essential for accelerating clinical adoption. However, strict regulations, gaps between research and clinical settings, and challenges in evaluating AI systems continue to hinder real-world implementation. This study presents an AI implementation case study within Shriners Childrens (SC), a large multisite pediatric system, showcasing the modernization of SCs Research Data Warehouse (RDW) to OMOP CDM v5.4 within a secure Microsoft Fabric environment. We introduce a Python-based data quality assessment tool compatible with SCs infrastructure, extending OHDsi's R/Java-based Data Quality Dashboard (DQD) and integrating Trustworthy AI principles using the METRIC framework. This extension enhances data quality evaluation by addressing informative missingness, redundancy, timeliness, and distributional consistency. We also compare systematic and case-specific AI implementation strategies for Craniofacial Microsomia (CFM) using the FHIR standard. Our contributions include a real-world evaluation of AI implementations, integration of Trustworthy AI principles into data quality assessment, and insights into hybrid implementation strategies that blend systematic infrastructure with use-case-driven approaches to advance AI in healthcare.
title An AI Implementation Science Study to Improve Trustworthy Data in a Large Healthcare System
topic Quantitative Methods
Machine Learning
I.2.1; H.2.1; J.3
url https://arxiv.org/abs/2512.03098