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Autori principali: Fontenot, Kelsey, Gorti, Anjali, Goel, Iva, Buonassisi, Tonio, Siemenn, Alexander E.
Natura: Preprint
Pubblicazione: 2025
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Accesso online:https://arxiv.org/abs/2512.06038
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author Fontenot, Kelsey
Gorti, Anjali
Goel, Iva
Buonassisi, Tonio
Siemenn, Alexander E.
author_facet Fontenot, Kelsey
Gorti, Anjali
Goel, Iva
Buonassisi, Tonio
Siemenn, Alexander E.
contents Self-driving laboratories (SDLs) have accelerated the throughput and automation capabilities for discovering and improving chemistries and materials. Although these SDLs have automated many of the steps required to conduct chemical and materials experiments, a commonly overlooked step in the automation pipeline is the handling and reloading of substrates used to transfer or deposit materials onto for downstream characterization. Here, we develop a closed-loop method of Automated Substrate Handling and Exchange (ASHE) using robotics, dual-actuated dispensers, and deep learning-driven computer vision to detect and correct errors in the manipulation of fragile and transparent substrates for SDLs. Using ASHE, we demonstrate a 98.5% first-time placement accuracy across 130 independent trials of reloading transparent glass substrates into an SDL, where only two substrate misplacements occurred and were successfully detected as errors and automatically corrected. Through the development of more accurate and reliable methods for handling various types of substrates, we move toward an improvement in the automation capabilities of self-driving laboratories, furthering the acceleration of novel chemical and materials discoveries.
format Preprint
id arxiv_https___arxiv_org_abs_2512_06038
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Closed-Loop Robotic Manipulation of Transparent Substrates for Self-Driving Laboratories using Deep Learning Micro-Error Correction
Fontenot, Kelsey
Gorti, Anjali
Goel, Iva
Buonassisi, Tonio
Siemenn, Alexander E.
Robotics
Machine Learning
Self-driving laboratories (SDLs) have accelerated the throughput and automation capabilities for discovering and improving chemistries and materials. Although these SDLs have automated many of the steps required to conduct chemical and materials experiments, a commonly overlooked step in the automation pipeline is the handling and reloading of substrates used to transfer or deposit materials onto for downstream characterization. Here, we develop a closed-loop method of Automated Substrate Handling and Exchange (ASHE) using robotics, dual-actuated dispensers, and deep learning-driven computer vision to detect and correct errors in the manipulation of fragile and transparent substrates for SDLs. Using ASHE, we demonstrate a 98.5% first-time placement accuracy across 130 independent trials of reloading transparent glass substrates into an SDL, where only two substrate misplacements occurred and were successfully detected as errors and automatically corrected. Through the development of more accurate and reliable methods for handling various types of substrates, we move toward an improvement in the automation capabilities of self-driving laboratories, furthering the acceleration of novel chemical and materials discoveries.
title Closed-Loop Robotic Manipulation of Transparent Substrates for Self-Driving Laboratories using Deep Learning Micro-Error Correction
topic Robotics
Machine Learning
url https://arxiv.org/abs/2512.06038