Machine Learning-based Unfolding for Cross Section Measurements in the Presence of Nuisance Parameters

Fuente: arXiv
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Autores principales: Zhu, Huanbiao, Desai, Krish, Kuusela, Mikael, Mikuni, Vinicius, Nachman, Benjamin, Wasserman, Larry
Formato: Preprint
Publicado: 2025
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author Zhu, Huanbiao
Desai, Krish
Kuusela, Mikael
Mikuni, Vinicius
Nachman, Benjamin
Wasserman, Larry
author_facet Zhu, Huanbiao
Desai, Krish
Kuusela, Mikael
Mikuni, Vinicius
Nachman, Benjamin
Wasserman, Larry
contents Statistically correcting measured cross sections for detector effects is an important step across many applications. In particle physics, this inverse problem is known as unfolding. In cases with complex instruments, the distortions they introduce are often known only implicitly through simulations of the detector. Modern machine learning has enabled efficient simulation-based approaches for unfolding high-dimensional data. Among these, one of the first methods successfully deployed on experimental data is the OmniFold algorithm, a classifier-based Expectation-Maximization procedure. In practice, however, the forward model is only approximately specified, and the corresponding uncertainty is encoded through nuisance parameters. Building on the well-studied OmniFold algorithm, we show how to extend machine learning-based unfolding to incorporate nuisance parameters. Our new algorithm, called Profile OmniFold, is demonstrated using a Gaussian example as well as a particle physics case study using simulated data from the CMS Experiment at the Large Hadron Collider.
format Preprint
id arxiv_https___arxiv_org_abs_2512_07074
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Machine Learning-based Unfolding for Cross Section Measurements in the Presence of Nuisance Parameters
Zhu, Huanbiao
Desai, Krish
Kuusela, Mikael
Mikuni, Vinicius
Nachman, Benjamin
Wasserman, Larry
Applications
High Energy Physics - Experiment
High Energy Physics - Phenomenology
Data Analysis, Statistics and Probability
Machine Learning
Statistically correcting measured cross sections for detector effects is an important step across many applications. In particle physics, this inverse problem is known as unfolding. In cases with complex instruments, the distortions they introduce are often known only implicitly through simulations of the detector. Modern machine learning has enabled efficient simulation-based approaches for unfolding high-dimensional data. Among these, one of the first methods successfully deployed on experimental data is the OmniFold algorithm, a classifier-based Expectation-Maximization procedure. In practice, however, the forward model is only approximately specified, and the corresponding uncertainty is encoded through nuisance parameters. Building on the well-studied OmniFold algorithm, we show how to extend machine learning-based unfolding to incorporate nuisance parameters. Our new algorithm, called Profile OmniFold, is demonstrated using a Gaussian example as well as a particle physics case study using simulated data from the CMS Experiment at the Large Hadron Collider.
title Machine Learning-based Unfolding for Cross Section Measurements in the Presence of Nuisance Parameters
topic Applications
High Energy Physics - Experiment
High Energy Physics - Phenomenology
Data Analysis, Statistics and Probability
Machine Learning
url https://arxiv.org/abs/2512.07074