Refuting "Debunking the GAMLSS Myth: Simplicity Reigns in Pulmonary Function Diagnostics"

Fuente: arXiv
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Auteurs principaux: Rigby, Robert A., Stasinopoulos, Mikis D., Zeileis, Achim, Stanojevic, Sanja, Heller, Gillian, de Bastiani, Fernanda, Kneib, Thomas, Mayr, Andreas, Stauffer, Reto, Umlauf, Nikolaus
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Publié: 2025
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author Rigby, Robert A.
Stasinopoulos, Mikis D.
Zeileis, Achim
Stanojevic, Sanja
Heller, Gillian
de Bastiani, Fernanda
Kneib, Thomas
Mayr, Andreas
Stauffer, Reto
Umlauf, Nikolaus
author_facet Rigby, Robert A.
Stasinopoulos, Mikis D.
Zeileis, Achim
Stanojevic, Sanja
Heller, Gillian
de Bastiani, Fernanda
Kneib, Thomas
Mayr, Andreas
Stauffer, Reto
Umlauf, Nikolaus
contents We read with interest the above article by Zavorsky (2025, Respiratory Medicine, doi:10.1016/j.rmed.2024.107836) concerning reference equations for pulmonary function testing. The author compares a Generalized Additive Model for Location, Scale, and Shape (GAMLSS), which is the standard adopted by the Global Lung Function Initiative (GLI), with a segmented linear regression (SLR) model, for pulmonary function variables. The author presents an interesting comparison; however there are some fundamental issues with the approach. We welcome this opportunity for discussion of the issues that it raises. The author's contention is that (1) SLR provides "prediction accuracies on par with GAMLSS"; and (2) the GAMLSS model equations are "complicated and require supplementary spline tables", whereas the SLR is "more straightforward, parsimonious, and accessible to a broader audience". We respectfully disagree with both of these points.
format Preprint
id arxiv_https___arxiv_org_abs_2512_09179
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Refuting "Debunking the GAMLSS Myth: Simplicity Reigns in Pulmonary Function Diagnostics"
Rigby, Robert A.
Stasinopoulos, Mikis D.
Zeileis, Achim
Stanojevic, Sanja
Heller, Gillian
de Bastiani, Fernanda
Kneib, Thomas
Mayr, Andreas
Stauffer, Reto
Umlauf, Nikolaus
Applications
We read with interest the above article by Zavorsky (2025, Respiratory Medicine, doi:10.1016/j.rmed.2024.107836) concerning reference equations for pulmonary function testing. The author compares a Generalized Additive Model for Location, Scale, and Shape (GAMLSS), which is the standard adopted by the Global Lung Function Initiative (GLI), with a segmented linear regression (SLR) model, for pulmonary function variables. The author presents an interesting comparison; however there are some fundamental issues with the approach. We welcome this opportunity for discussion of the issues that it raises. The author's contention is that (1) SLR provides "prediction accuracies on par with GAMLSS"; and (2) the GAMLSS model equations are "complicated and require supplementary spline tables", whereas the SLR is "more straightforward, parsimonious, and accessible to a broader audience". We respectfully disagree with both of these points.
title Refuting "Debunking the GAMLSS Myth: Simplicity Reigns in Pulmonary Function Diagnostics"
topic Applications
url https://arxiv.org/abs/2512.09179