Modality-Specific Enhancement and Complementary Fusion for Semi-Supervised Multi-Modal Brain Tumor Segmentation

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Hauptverfasser: Chung, Tien-Dat, Lam, Ba-Thinh, Nguyen, Thanh-Huy, Nguyen, Thien, Vu, Nguyen Lan Vi, Cao, Hoang-Loc, Huynh, Phat Kim, Xu, Min
Format: Preprint
Veröffentlicht: 2025
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author Chung, Tien-Dat
Lam, Ba-Thinh
Nguyen, Thanh-Huy
Nguyen, Thien
Vu, Nguyen Lan Vi
Cao, Hoang-Loc
Huynh, Phat Kim
Xu, Min
author_facet Chung, Tien-Dat
Lam, Ba-Thinh
Nguyen, Thanh-Huy
Nguyen, Thien
Vu, Nguyen Lan Vi
Cao, Hoang-Loc
Huynh, Phat Kim
Xu, Min
contents Semi-supervised learning (SSL) has become a promising direction for medical image segmentation, enabling models to learn from limited labeled data alongside abundant unlabeled samples. However, existing SSL approaches for multi-modal medical imaging often struggle to exploit the complementary information between modalities due to semantic discrepancies and misalignment across MRI sequences. To address this, we propose a novel semi-supervised multi-modal framework that explicitly enhances modality-specific representations and facilitates adaptive cross-modal information fusion. Specifically, we introduce a Modality-specific Enhancing Module (MEM) to strengthen semantic cues unique to each modality via channel-wise attention, and a learnable Complementary Information Fusion (CIF) module to adaptively exchange complementary knowledge between modalities. The overall framework is optimized using a hybrid objective combining supervised segmentation loss and cross-modal consistency regularization on unlabeled data. Extensive experiments on the BraTS 2019 (HGG subset) demonstrate that our method consistently outperforms strong semi-supervised and multi-modal baselines under 1\%, 5\%, and 10\% labeled data settings, achieving significant improvements in both Dice and Sensitivity scores. Ablation studies further confirm the complementary effects of our proposed MEM and CIF in bridging cross-modality discrepancies and improving segmentation robustness under scarce supervision.
format Preprint
id arxiv_https___arxiv_org_abs_2512_09801
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Modality-Specific Enhancement and Complementary Fusion for Semi-Supervised Multi-Modal Brain Tumor Segmentation
Chung, Tien-Dat
Lam, Ba-Thinh
Nguyen, Thanh-Huy
Nguyen, Thien
Vu, Nguyen Lan Vi
Cao, Hoang-Loc
Huynh, Phat Kim
Xu, Min
Computer Vision and Pattern Recognition
Semi-supervised learning (SSL) has become a promising direction for medical image segmentation, enabling models to learn from limited labeled data alongside abundant unlabeled samples. However, existing SSL approaches for multi-modal medical imaging often struggle to exploit the complementary information between modalities due to semantic discrepancies and misalignment across MRI sequences. To address this, we propose a novel semi-supervised multi-modal framework that explicitly enhances modality-specific representations and facilitates adaptive cross-modal information fusion. Specifically, we introduce a Modality-specific Enhancing Module (MEM) to strengthen semantic cues unique to each modality via channel-wise attention, and a learnable Complementary Information Fusion (CIF) module to adaptively exchange complementary knowledge between modalities. The overall framework is optimized using a hybrid objective combining supervised segmentation loss and cross-modal consistency regularization on unlabeled data. Extensive experiments on the BraTS 2019 (HGG subset) demonstrate that our method consistently outperforms strong semi-supervised and multi-modal baselines under 1\%, 5\%, and 10\% labeled data settings, achieving significant improvements in both Dice and Sensitivity scores. Ablation studies further confirm the complementary effects of our proposed MEM and CIF in bridging cross-modality discrepancies and improving segmentation robustness under scarce supervision.
title Modality-Specific Enhancement and Complementary Fusion for Semi-Supervised Multi-Modal Brain Tumor Segmentation
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2512.09801