KRAS G12D protein screening for pancreatic cancer clinical trials using an AlGaN/GaN high electron mobility transistor biosensor
Fuente:
arXiv
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| Autores principales: | , , , , , , , , , |
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| Formato: | Preprint |
| Publicado: |
2025
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| Materias: | |
| Acceso en línea: | |
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| _version_ | 1866914387342655488 |
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| author | Hung, Sheng-Ting Lee, Cheng Yan Lien, Chen-Yu Chan, Cheng-Hsuan Yang, Ya-Han Chen, Quark Yungsung Cheng, Kuang-Hung Kuo, Kung-Kai Tu, Li-Wei Chang, Ching-Wen |
| author_facet | Hung, Sheng-Ting Lee, Cheng Yan Lien, Chen-Yu Chan, Cheng-Hsuan Yang, Ya-Han Chen, Quark Yungsung Cheng, Kuang-Hung Kuo, Kung-Kai Tu, Li-Wei Chang, Ching-Wen |
| contents | Clinical trials screening KRAS G12D protein for 30 pancreatic ductal adenocarcinoma (PDAC) patients and 30 healthy donors were conducted utilizing an AlGaN/GaN high electron mobility transistor (HEMT) biosensor. All resistance change ratios of PDAC patients are higher than the standard deviation above the mean resistance change ratio obtained from all healthy donors. The results demonstrate the effectiveness of the HEMT biosensor and reveal its potential for early detection of pancreatic cancer with KRAS G12D protein screening. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2512_10377 |
| institution | arXiv |
| publishDate | 2025 |
| record_format | arxiv |
| spellingShingle | KRAS G12D protein screening for pancreatic cancer clinical trials using an AlGaN/GaN high electron mobility transistor biosensor Hung, Sheng-Ting Lee, Cheng Yan Lien, Chen-Yu Chan, Cheng-Hsuan Yang, Ya-Han Chen, Quark Yungsung Cheng, Kuang-Hung Kuo, Kung-Kai Tu, Li-Wei Chang, Ching-Wen Medical Physics Clinical trials screening KRAS G12D protein for 30 pancreatic ductal adenocarcinoma (PDAC) patients and 30 healthy donors were conducted utilizing an AlGaN/GaN high electron mobility transistor (HEMT) biosensor. All resistance change ratios of PDAC patients are higher than the standard deviation above the mean resistance change ratio obtained from all healthy donors. The results demonstrate the effectiveness of the HEMT biosensor and reveal its potential for early detection of pancreatic cancer with KRAS G12D protein screening. |
| title | KRAS G12D protein screening for pancreatic cancer clinical trials using an AlGaN/GaN high electron mobility transistor biosensor |
| topic | Medical Physics |
| url | https://arxiv.org/abs/2512.10377 |