Robust Multi-Disease Retinal Classification via Xception-Based Transfer Learning and W-Net Vessel Segmentation

Fuente: arXiv
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Auteurs principaux: Gholizadeh, Mohammad Sadegh, Rezapour, Amir Arsalan
Format: Preprint
Publié: 2025
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author Gholizadeh, Mohammad Sadegh
Rezapour, Amir Arsalan
author_facet Gholizadeh, Mohammad Sadegh
Rezapour, Amir Arsalan
contents In recent years, the incidence of vision-threatening eye diseases has risen dramatically, necessitating scalable and accurate screening solutions. This paper presents a comprehensive study on deep learning architectures for the automated diagnosis of ocular conditions. To mitigate the "black-box" limitations of standard convolutional neural networks (CNNs), we implement a pipeline that combines deep feature extraction with interpretable image processing modules. Specifically, we focus on high-fidelity retinal vessel segmentation as an auxiliary task to guide the classification process. By grounding the model's predictions in clinically relevant morphological features, we aim to bridge the gap between algorithmic output and expert medical validation, thereby reducing false positives and improving deployment viability in clinical settings.
format Preprint
id arxiv_https___arxiv_org_abs_2512_10608
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Robust Multi-Disease Retinal Classification via Xception-Based Transfer Learning and W-Net Vessel Segmentation
Gholizadeh, Mohammad Sadegh
Rezapour, Amir Arsalan
Computer Vision and Pattern Recognition
In recent years, the incidence of vision-threatening eye diseases has risen dramatically, necessitating scalable and accurate screening solutions. This paper presents a comprehensive study on deep learning architectures for the automated diagnosis of ocular conditions. To mitigate the "black-box" limitations of standard convolutional neural networks (CNNs), we implement a pipeline that combines deep feature extraction with interpretable image processing modules. Specifically, we focus on high-fidelity retinal vessel segmentation as an auxiliary task to guide the classification process. By grounding the model's predictions in clinically relevant morphological features, we aim to bridge the gap between algorithmic output and expert medical validation, thereby reducing false positives and improving deployment viability in clinical settings.
title Robust Multi-Disease Retinal Classification via Xception-Based Transfer Learning and W-Net Vessel Segmentation
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2512.10608