Dynamical analysis in a nonlocal delayed reaction-diffusion tumor model with therapy

Fuente: arXiv
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Autori principali: Hu, Dandan, Yuan, Yuan
Natura: Preprint
Pubblicazione: 2025
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author Hu, Dandan
Yuan, Yuan
author_facet Hu, Dandan
Yuan, Yuan
contents In this work, we investigate the dynamical properties of a reaction-diffusion system arising from tumor-therapy modelling that features both nonlinear interactions and nonlocal delay. By applying the Lyapunov-Schmidt reduction, we establish the existence of a nontrivial steady-state solution bifurcating from the trivial solution. In particular, we derive an approximate expression for a spatially nonhomogeneous steady-state solution. Then, we provide a detailed spectral characterization of the linearized operator and explicit stability criteria and identify the delay-dependent Hopf bifurcation regimes. To illustrate the theoretical results, we include a concrete example that verifies the claims in our theorems and numerically demonstrates how changes in treatment parameters alter stability and bifurcation behaviour.
format Preprint
id arxiv_https___arxiv_org_abs_2512_13831
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Dynamical analysis in a nonlocal delayed reaction-diffusion tumor model with therapy
Hu, Dandan
Yuan, Yuan
Dynamical Systems
34K18, 35B32, 35B35, 35K57, 35Q92
In this work, we investigate the dynamical properties of a reaction-diffusion system arising from tumor-therapy modelling that features both nonlinear interactions and nonlocal delay. By applying the Lyapunov-Schmidt reduction, we establish the existence of a nontrivial steady-state solution bifurcating from the trivial solution. In particular, we derive an approximate expression for a spatially nonhomogeneous steady-state solution. Then, we provide a detailed spectral characterization of the linearized operator and explicit stability criteria and identify the delay-dependent Hopf bifurcation regimes. To illustrate the theoretical results, we include a concrete example that verifies the claims in our theorems and numerically demonstrates how changes in treatment parameters alter stability and bifurcation behaviour.
title Dynamical analysis in a nonlocal delayed reaction-diffusion tumor model with therapy
topic Dynamical Systems
34K18, 35B32, 35B35, 35K57, 35Q92
url https://arxiv.org/abs/2512.13831