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Main Authors: Fu, Yibing, Zhao, Yunpeng, Zeng, Zhitao, Chen, Cheng, Jin, Yueming
Format: Preprint
Published: 2025
Subjects:
Online Access:https://arxiv.org/abs/2512.14026
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author Fu, Yibing
Zhao, Yunpeng
Zeng, Zhitao
Chen, Cheng
Jin, Yueming
author_facet Fu, Yibing
Zhao, Yunpeng
Zeng, Zhitao
Chen, Cheng
Jin, Yueming
contents Multi-modal learning integrating medical images and tabular data has significantly advanced clinical decision-making in recent years. Self-Supervised Learning (SSL) has emerged as a powerful paradigm for pretraining these models on large-scale unlabeled image-tabular data, aiming to learn discriminative representations. However, existing SSL methods for image-tabular representation learning are often confined to specific data cohorts, mainly due to their rigid tabular modeling mechanisms when modeling heterogeneous tabular data. This inter-tabular barrier hinders the multi-modal SSL methods from effectively learning transferrable medical knowledge shared across diverse cohorts. In this paper, we propose a novel SSL framework, namely CITab, designed to learn powerful multi-modal feature representations in a cross-tabular manner. We design the tabular modeling mechanism from a semantic-awareness perspective by integrating column headers as semantic cues, which facilitates transferrable knowledge learning and the scalability in utilizing multiple data sources for pretraining. Additionally, we propose a prototype-guided mixture-of-linear layer (P-MoLin) module for tabular feature specialization, empowering the model to effectively handle the heterogeneity of tabular data and explore the underlying medical concepts. We conduct comprehensive evaluations on Alzheimer's disease diagnosis task across three publicly available data cohorts containing 4,461 subjects. Experimental results demonstrate that CITab outperforms state-of-the-art approaches, paving the way for effective and scalable cross-tabular multi-modal learning.
format Preprint
id arxiv_https___arxiv_org_abs_2512_14026
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Unleashing the Power of Image-Tabular Self-Supervised Learning via Breaking Cross-Tabular Barriers
Fu, Yibing
Zhao, Yunpeng
Zeng, Zhitao
Chen, Cheng
Jin, Yueming
Computer Vision and Pattern Recognition
Multi-modal learning integrating medical images and tabular data has significantly advanced clinical decision-making in recent years. Self-Supervised Learning (SSL) has emerged as a powerful paradigm for pretraining these models on large-scale unlabeled image-tabular data, aiming to learn discriminative representations. However, existing SSL methods for image-tabular representation learning are often confined to specific data cohorts, mainly due to their rigid tabular modeling mechanisms when modeling heterogeneous tabular data. This inter-tabular barrier hinders the multi-modal SSL methods from effectively learning transferrable medical knowledge shared across diverse cohorts. In this paper, we propose a novel SSL framework, namely CITab, designed to learn powerful multi-modal feature representations in a cross-tabular manner. We design the tabular modeling mechanism from a semantic-awareness perspective by integrating column headers as semantic cues, which facilitates transferrable knowledge learning and the scalability in utilizing multiple data sources for pretraining. Additionally, we propose a prototype-guided mixture-of-linear layer (P-MoLin) module for tabular feature specialization, empowering the model to effectively handle the heterogeneity of tabular data and explore the underlying medical concepts. We conduct comprehensive evaluations on Alzheimer's disease diagnosis task across three publicly available data cohorts containing 4,461 subjects. Experimental results demonstrate that CITab outperforms state-of-the-art approaches, paving the way for effective and scalable cross-tabular multi-modal learning.
title Unleashing the Power of Image-Tabular Self-Supervised Learning via Breaking Cross-Tabular Barriers
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2512.14026