Enhancing Alzheimer's Detection through Late Fusion of Multi-Modal EEG Features

Fuente: arXiv
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Main Authors: Vinh, Nguyen Thanh, Vishwanath, Manoj, Nguyen-Quang, Thinh, Ha, Nguyen Viet, Tung, Bui Thanh, Han, Huy-Dung, Linh, Nguyen Quang, Linh, Nguyen Hai, Cao, Hung
Format: Preprint
Published: 2025
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author Vinh, Nguyen Thanh
Vishwanath, Manoj
Nguyen-Quang, Thinh
Ha, Nguyen Viet
Tung, Bui Thanh
Han, Huy-Dung
Linh, Nguyen Quang
Linh, Nguyen Hai
Cao, Hung
author_facet Vinh, Nguyen Thanh
Vishwanath, Manoj
Nguyen-Quang, Thinh
Ha, Nguyen Viet
Tung, Bui Thanh
Han, Huy-Dung
Linh, Nguyen Quang
Linh, Nguyen Hai
Cao, Hung
contents Alzheimer s disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline, where early detection is essential for timely intervention and improved patient outcomes. Traditional diagnostic methods are time-consuming and require expert interpretation, thus, automated approaches are highly desirable. This study presents a novel deep learning framework for AD diagnosis using Electroencephalograph (EEG) signals, integrating multiple feature extraction techniques including alpha-wave analysis, Discrete Wavelet Transform (DWT), and Markov Transition Fields (MTF). A late-fusion strategy is employed to combine predictions from separate neural networks trained on these diverse representations, capturing both temporal and frequency-domain patterns in the EEG data. The proposed model attains a classification accuracy of 87.23%, with a precision of 87.95%, a recall of 86.91%, and an F1 score of 87.42% when evaluated on a publicly available dataset, demonstrating its potential for reliable, scalable, and early AD screening. Rigorous preprocessing and targeted frequency band selection, particularly in the alpha range due to its cognitive relevance, further enhance performance. This work highlights the promise of deep learning in supporting physicians with efficient and accessible tools for early AD diagnosis.
format Preprint
id arxiv_https___arxiv_org_abs_2512_15246
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Enhancing Alzheimer's Detection through Late Fusion of Multi-Modal EEG Features
Vinh, Nguyen Thanh
Vishwanath, Manoj
Nguyen-Quang, Thinh
Ha, Nguyen Viet
Tung, Bui Thanh
Han, Huy-Dung
Linh, Nguyen Quang
Linh, Nguyen Hai
Cao, Hung
Signal Processing
Alzheimer s disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline, where early detection is essential for timely intervention and improved patient outcomes. Traditional diagnostic methods are time-consuming and require expert interpretation, thus, automated approaches are highly desirable. This study presents a novel deep learning framework for AD diagnosis using Electroencephalograph (EEG) signals, integrating multiple feature extraction techniques including alpha-wave analysis, Discrete Wavelet Transform (DWT), and Markov Transition Fields (MTF). A late-fusion strategy is employed to combine predictions from separate neural networks trained on these diverse representations, capturing both temporal and frequency-domain patterns in the EEG data. The proposed model attains a classification accuracy of 87.23%, with a precision of 87.95%, a recall of 86.91%, and an F1 score of 87.42% when evaluated on a publicly available dataset, demonstrating its potential for reliable, scalable, and early AD screening. Rigorous preprocessing and targeted frequency band selection, particularly in the alpha range due to its cognitive relevance, further enhance performance. This work highlights the promise of deep learning in supporting physicians with efficient and accessible tools for early AD diagnosis.
title Enhancing Alzheimer's Detection through Late Fusion of Multi-Modal EEG Features
topic Signal Processing
url https://arxiv.org/abs/2512.15246