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| Main Authors: | , , , , , |
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| Format: | Preprint |
| Published: |
2025
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| Subjects: | |
| Online Access: | https://arxiv.org/abs/2512.15762 |
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| _version_ | 1866912979760447488 |
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| author | Li, Kanxue Zhan, Yibing Jin, Hua Qi, Chongchong Lin, Xu Yu, Baosheng |
| author_facet | Li, Kanxue Zhan, Yibing Jin, Hua Qi, Chongchong Lin, Xu Yu, Baosheng |
| contents | Intraoperative hypotension (IOH) poses significant surgical risks, but accurate prediction remains challenging due to patient-specific variability. While test-time adaptation (TTA) offers a promising approach for personalized prediction, the rarity of IOH events often leads to unreliable test-time training. To address this, we propose CSA-TTA, a novel Cross-Sample Augmented Test-Time Adaptation framework that enhances training by incorporating hypotension events from other individuals. Specifically, we first construct a cross-sample bank by segmenting historical data into hypotensive and non-hypotensive samples. Then, we introduce a coarse-to-fine retrieval strategy for building test-time training data: we initially apply K-Shape clustering to identify representative cluster centers and subsequently retrieve the top-K semantically similar samples based on the current patient signal. Additionally, we integrate both self-supervised masked reconstruction and retrospective sequence forecasting signals during training to enhance model adaptability to rapid and subtle intraoperative dynamics. We evaluate the proposed CSA-TTA on both the VitalDB dataset and a real-world in-hospital dataset by integrating it with state-of-the-art time series forecasting models, including TimesFM and UniTS. CSA-TTA consistently enhances performance across settings-for instance, on VitalDB, it improves Recall and F1 scores by +1.33% and +1.13%, respectively, under fine-tuning, and by +7.46% and +5.07% in zero-shot scenarios-demonstrating strong robustness and generalization. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2512_15762 |
| institution | arXiv |
| publishDate | 2025 |
| record_format | arxiv |
| spellingShingle | Cross-Sample Augmented Test-Time Adaptation for Personalized Intraoperative Hypotension Prediction Li, Kanxue Zhan, Yibing Jin, Hua Qi, Chongchong Lin, Xu Yu, Baosheng Machine Learning Artificial Intelligence Intraoperative hypotension (IOH) poses significant surgical risks, but accurate prediction remains challenging due to patient-specific variability. While test-time adaptation (TTA) offers a promising approach for personalized prediction, the rarity of IOH events often leads to unreliable test-time training. To address this, we propose CSA-TTA, a novel Cross-Sample Augmented Test-Time Adaptation framework that enhances training by incorporating hypotension events from other individuals. Specifically, we first construct a cross-sample bank by segmenting historical data into hypotensive and non-hypotensive samples. Then, we introduce a coarse-to-fine retrieval strategy for building test-time training data: we initially apply K-Shape clustering to identify representative cluster centers and subsequently retrieve the top-K semantically similar samples based on the current patient signal. Additionally, we integrate both self-supervised masked reconstruction and retrospective sequence forecasting signals during training to enhance model adaptability to rapid and subtle intraoperative dynamics. We evaluate the proposed CSA-TTA on both the VitalDB dataset and a real-world in-hospital dataset by integrating it with state-of-the-art time series forecasting models, including TimesFM and UniTS. CSA-TTA consistently enhances performance across settings-for instance, on VitalDB, it improves Recall and F1 scores by +1.33% and +1.13%, respectively, under fine-tuning, and by +7.46% and +5.07% in zero-shot scenarios-demonstrating strong robustness and generalization. |
| title | Cross-Sample Augmented Test-Time Adaptation for Personalized Intraoperative Hypotension Prediction |
| topic | Machine Learning Artificial Intelligence |
| url | https://arxiv.org/abs/2512.15762 |