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| Format: | Preprint |
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2025
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| Online Access: | https://arxiv.org/abs/2512.15828 |
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| _version_ | 1866918254123941888 |
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| author | Nunns, Henry Riehl, Manda |
| author_facet | Nunns, Henry Riehl, Manda |
| contents | In this paper we present two modifications of traditional $NK$ fitness landscapes, the $θNK$ and $HNK$ models, and explore these modifications via accessibility and ruggedness. The $θNK$ model introduces a parameter $θ$ to integrate local Rough Mount Fuji-type correlations in subgenotype contributions, simulating more biologically realistic correlated fitness effects. The $HNK$ model incorporates gene regulation effects by introducing a masking mechanism where certain loci modulate the expression of other loci, simulating effects observed in gene regulatory networks without modeling the full network. Through extensive simulations across a wide range of parameters ($N$, $K$, $θ$, and $H$), we analyze the impact of these modifications on landscape accessibility and the number of local optima. We find that increasing $θ$ or the number of masking loci ($H$) generally enhances accessibility, even in landscapes with many local optima, showing that ruggedness doesn't necessarily hinder evolutionary pathways. Additionally, distinct interaction patterns (blocked, adjacent, random) lead to different observations in accessibility and optimum structure. While more complex than traditional $NK$, we believe each model provides a new biologically relevant facet to fitness landscapes and provides insight into how genetic and regulatory structures influence the evolutionary potential of populations. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2512_15828 |
| institution | arXiv |
| publishDate | 2025 |
| record_format | arxiv |
| spellingShingle | Accessibility of Modified NK Fitness Landscapes Nunns, Henry Riehl, Manda Quantitative Methods 92-10, 06B99 In this paper we present two modifications of traditional $NK$ fitness landscapes, the $θNK$ and $HNK$ models, and explore these modifications via accessibility and ruggedness. The $θNK$ model introduces a parameter $θ$ to integrate local Rough Mount Fuji-type correlations in subgenotype contributions, simulating more biologically realistic correlated fitness effects. The $HNK$ model incorporates gene regulation effects by introducing a masking mechanism where certain loci modulate the expression of other loci, simulating effects observed in gene regulatory networks without modeling the full network. Through extensive simulations across a wide range of parameters ($N$, $K$, $θ$, and $H$), we analyze the impact of these modifications on landscape accessibility and the number of local optima. We find that increasing $θ$ or the number of masking loci ($H$) generally enhances accessibility, even in landscapes with many local optima, showing that ruggedness doesn't necessarily hinder evolutionary pathways. Additionally, distinct interaction patterns (blocked, adjacent, random) lead to different observations in accessibility and optimum structure. While more complex than traditional $NK$, we believe each model provides a new biologically relevant facet to fitness landscapes and provides insight into how genetic and regulatory structures influence the evolutionary potential of populations. |
| title | Accessibility of Modified NK Fitness Landscapes |
| topic | Quantitative Methods 92-10, 06B99 |
| url | https://arxiv.org/abs/2512.15828 |