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Bibliographic Details
Main Authors: Weinstein, Eli N., Slabodkin, Andrei, Gollub, Mattia G., Dobbs, Kerry, Cui, Xiao-Bing, Zhang, Fang, Gurung, Kristina, Wood, Elizabeth B.
Format: Preprint
Published: 2025
Subjects:
Online Access:https://arxiv.org/abs/2512.15984
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Table of Contents:
  • One strategy to scale up ML-driven science is to increase wet lab experiments' information density. We present a method based on a neural extension of compressed sensing to function space. We measure the activity of multiple different molecules simultaneously, rather than individually. Then, we deconvolute the molecule-activity map during model training. Co-design of wet lab experiments and learning algorithms provably leads to orders-of-magnitude gains in information density. We demonstrate on antibodies and cell therapies.