Enhancing Medical Large Vision-Language Models via Alignment Distillation

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Autori principali: Chang, Aofei, Wang, Ting, Ma, Fenglong
Natura: Preprint
Pubblicazione: 2025
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author Chang, Aofei
Wang, Ting
Ma, Fenglong
author_facet Chang, Aofei
Wang, Ting
Ma, Fenglong
contents Medical Large Vision-Language Models (Med-LVLMs) have shown promising results in clinical applications, but often suffer from hallucinated outputs due to misaligned visual understanding. In this work, we identify two fundamental limitations contributing to this issue: insufficient visual representation learning and poor visual attention alignment. To address these problems, we propose MEDALIGN, a simple, lightweight alignment distillation framework that transfers visual alignment knowledge from a domain-specific Contrastive Language-Image Pre-training (CLIP) model to Med-LVLMs. MEDALIGN introduces two distillation losses: a spatial-aware visual alignment loss based on visual token-level similarity structures, and an attention-aware distillation loss that guides attention toward diagnostically relevant regions. Extensive experiments on medical report generation and medical visual question answering (VQA) benchmarks show that MEDALIGN consistently improves both performance and interpretability, yielding more visually grounded outputs.
format Preprint
id arxiv_https___arxiv_org_abs_2512_18554
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Enhancing Medical Large Vision-Language Models via Alignment Distillation
Chang, Aofei
Wang, Ting
Ma, Fenglong
Computer Vision and Pattern Recognition
Artificial Intelligence
Medical Large Vision-Language Models (Med-LVLMs) have shown promising results in clinical applications, but often suffer from hallucinated outputs due to misaligned visual understanding. In this work, we identify two fundamental limitations contributing to this issue: insufficient visual representation learning and poor visual attention alignment. To address these problems, we propose MEDALIGN, a simple, lightweight alignment distillation framework that transfers visual alignment knowledge from a domain-specific Contrastive Language-Image Pre-training (CLIP) model to Med-LVLMs. MEDALIGN introduces two distillation losses: a spatial-aware visual alignment loss based on visual token-level similarity structures, and an attention-aware distillation loss that guides attention toward diagnostically relevant regions. Extensive experiments on medical report generation and medical visual question answering (VQA) benchmarks show that MEDALIGN consistently improves both performance and interpretability, yielding more visually grounded outputs.
title Enhancing Medical Large Vision-Language Models via Alignment Distillation
topic Computer Vision and Pattern Recognition
Artificial Intelligence
url https://arxiv.org/abs/2512.18554