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Main Authors: Safari, Mojtaba, Wang, Shansong, Wildman, Vanessa L, Hu, Mingzhe, Eidex, Zach, Chang, Chih-Wei, Middlebrooks, Erik H, Qiu, Richard L. J, Patel, Pretesh, Jani, Ashesh B., Mao, Hui, Tian, Zhen, Yang, Xiaofeng
Format: Preprint
Published: 2025
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Online Access:https://arxiv.org/abs/2512.19676
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author Safari, Mojtaba
Wang, Shansong
Wildman, Vanessa L
Hu, Mingzhe
Eidex, Zach
Chang, Chih-Wei
Middlebrooks, Erik H
Qiu, Richard L. J
Patel, Pretesh
Jani, Ashesh B.
Mao, Hui
Tian, Zhen
Yang, Xiaofeng
author_facet Safari, Mojtaba
Wang, Shansong
Wildman, Vanessa L
Hu, Mingzhe
Eidex, Zach
Chang, Chih-Wei
Middlebrooks, Erik H
Qiu, Richard L. J
Patel, Pretesh
Jani, Ashesh B.
Mao, Hui
Tian, Zhen
Yang, Xiaofeng
contents Background: High-resolution MRI is critical for diagnosis, but long acquisition times limit clinical use. Super-resolution (SR) can enhance resolution post-scan, yet existing deep learning methods face fidelity-efficiency trade-offs. Purpose: To develop a computationally efficient and accurate deep learning framework for MRI SR that preserves anatomical detail for clinical integration. Materials and Methods: We propose a novel SR framework combining multi-head selective state-space models (MHSSM) with a lightweight channel MLP. The model uses 2D patch extraction with hybrid scanning to capture long-range dependencies. Each MambaFormer block integrates MHSSM, depthwise convolutions, and gated channel mixing. Evaluation used 7T brain T1 MP2RAGE maps (n=142) and 1.5T prostate T2w MRI (n=334). Comparisons included Bicubic interpolation, GANs (CycleGAN, Pix2pix, SPSR), transformers (SwinIR), Mamba (MambaIR), and diffusion models (I2SB, Res-SRDiff). Results: Our model achieved superior performance with exceptional efficiency. For 7T brain data: SSIM=0.951+-0.021, PSNR=26.90+-1.41 dB, LPIPS=0.076+-0.022, GMSD=0.083+-0.017, significantly outperforming all baselines (p<0.001). For prostate data: SSIM=0.770+-0.049, PSNR=27.15+-2.19 dB, LPIPS=0.190+-0.095, GMSD=0.087+-0.013. The framework used only 0.9M parameters and 57 GFLOPs, reducing parameters by 99.8% and computation by 97.5% versus Res-SRDiff, while outperforming SwinIR and MambaIR in accuracy and efficiency. Conclusion: The proposed framework provides an efficient, accurate MRI SR solution, delivering enhanced anatomical detail across datasets. Its low computational demand and state-of-the-art performance show strong potential for clinical translation.
format Preprint
id arxiv_https___arxiv_org_abs_2512_19676
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Efficient Vision Mamba for MRI Super-Resolution via Hybrid Selective Scanning
Safari, Mojtaba
Wang, Shansong
Wildman, Vanessa L
Hu, Mingzhe
Eidex, Zach
Chang, Chih-Wei
Middlebrooks, Erik H
Qiu, Richard L. J
Patel, Pretesh
Jani, Ashesh B.
Mao, Hui
Tian, Zhen
Yang, Xiaofeng
Computer Vision and Pattern Recognition
Medical Physics
Background: High-resolution MRI is critical for diagnosis, but long acquisition times limit clinical use. Super-resolution (SR) can enhance resolution post-scan, yet existing deep learning methods face fidelity-efficiency trade-offs. Purpose: To develop a computationally efficient and accurate deep learning framework for MRI SR that preserves anatomical detail for clinical integration. Materials and Methods: We propose a novel SR framework combining multi-head selective state-space models (MHSSM) with a lightweight channel MLP. The model uses 2D patch extraction with hybrid scanning to capture long-range dependencies. Each MambaFormer block integrates MHSSM, depthwise convolutions, and gated channel mixing. Evaluation used 7T brain T1 MP2RAGE maps (n=142) and 1.5T prostate T2w MRI (n=334). Comparisons included Bicubic interpolation, GANs (CycleGAN, Pix2pix, SPSR), transformers (SwinIR), Mamba (MambaIR), and diffusion models (I2SB, Res-SRDiff). Results: Our model achieved superior performance with exceptional efficiency. For 7T brain data: SSIM=0.951+-0.021, PSNR=26.90+-1.41 dB, LPIPS=0.076+-0.022, GMSD=0.083+-0.017, significantly outperforming all baselines (p<0.001). For prostate data: SSIM=0.770+-0.049, PSNR=27.15+-2.19 dB, LPIPS=0.190+-0.095, GMSD=0.087+-0.013. The framework used only 0.9M parameters and 57 GFLOPs, reducing parameters by 99.8% and computation by 97.5% versus Res-SRDiff, while outperforming SwinIR and MambaIR in accuracy and efficiency. Conclusion: The proposed framework provides an efficient, accurate MRI SR solution, delivering enhanced anatomical detail across datasets. Its low computational demand and state-of-the-art performance show strong potential for clinical translation.
title Efficient Vision Mamba for MRI Super-Resolution via Hybrid Selective Scanning
topic Computer Vision and Pattern Recognition
Medical Physics
url https://arxiv.org/abs/2512.19676