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Main Authors: Qin, Ziwei, Song, Xuhui, Huang, Deqing, Qin, Na, Li, Jun
Format: Preprint
Published: 2025
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Online Access:https://arxiv.org/abs/2512.20026
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author Qin, Ziwei
Song, Xuhui
Huang, Deqing
Qin, Na
Li, Jun
author_facet Qin, Ziwei
Song, Xuhui
Huang, Deqing
Qin, Na
Li, Jun
contents Graph neural networks are increasingly applied to multimodal medical diagnosis for their inherent relational modeling capabilities. However, their efficacy is often compromised by the prevailing reliance on a single, static graph built from indiscriminate features, hindering the ability to model patient-specific pathological relationships. To this end, the proposed Multi-Activation Plane Interaction Graph Neural Network (MAPI-GNN) reconstructs this single-graph paradigm by learning a multifaceted graph profile from semantically disentangled feature subspaces. The framework first uncovers latent graph-aware patterns via a multi-dimensional discriminator; these patterns then guide the dynamic construction of a stack of activation graphs; and this multifaceted profile is finally aggregated and contextualized by a relational fusion engine for a robust diagnosis. Extensive experiments on two diverse tasks, comprising over 1300 patient samples, demonstrate that MAPI-GNN significantly outperforms state-of-the-art methods.
format Preprint
id arxiv_https___arxiv_org_abs_2512_20026
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle MAPI-GNN: Multi-Activation Plane Interaction Graph Neural Network for Multimodal Medical Diagnosis
Qin, Ziwei
Song, Xuhui
Huang, Deqing
Qin, Na
Li, Jun
Computer Vision and Pattern Recognition
Graph neural networks are increasingly applied to multimodal medical diagnosis for their inherent relational modeling capabilities. However, their efficacy is often compromised by the prevailing reliance on a single, static graph built from indiscriminate features, hindering the ability to model patient-specific pathological relationships. To this end, the proposed Multi-Activation Plane Interaction Graph Neural Network (MAPI-GNN) reconstructs this single-graph paradigm by learning a multifaceted graph profile from semantically disentangled feature subspaces. The framework first uncovers latent graph-aware patterns via a multi-dimensional discriminator; these patterns then guide the dynamic construction of a stack of activation graphs; and this multifaceted profile is finally aggregated and contextualized by a relational fusion engine for a robust diagnosis. Extensive experiments on two diverse tasks, comprising over 1300 patient samples, demonstrate that MAPI-GNN significantly outperforms state-of-the-art methods.
title MAPI-GNN: Multi-Activation Plane Interaction Graph Neural Network for Multimodal Medical Diagnosis
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2512.20026