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Main Authors: Yang, Xinquan, Xie, Jinheng, Huang, Yawen, Li, Yuexiang, Huang, Huimin, Zheng, Hao, Wu, Xian, Zheng, Yefeng, Shen, Linlin
Format: Preprint
Published: 2025
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Online Access:https://arxiv.org/abs/2512.20980
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author Yang, Xinquan
Xie, Jinheng
Huang, Yawen
Li, Yuexiang
Huang, Huimin
Zheng, Hao
Wu, Xian
Zheng, Yefeng
Shen, Linlin
author_facet Yang, Xinquan
Xie, Jinheng
Huang, Yawen
Li, Yuexiang
Huang, Huimin
Zheng, Hao
Wu, Xian
Zheng, Yefeng
Shen, Linlin
contents Long-tailed pulmonary anomalies in chest radiography present formidable diagnostic challenges. Despite the recent strides in diffusion-based methods for enhancing the representation of tailed lesions, the paucity of rare lesion exemplars curtails the generative capabilities of these approaches, thereby leaving the diagnostic precision less than optimal. In this paper, we propose a novel data synthesis pipeline designed to augment tail lesions utilizing a copious supply of conventional normal X-rays. Specifically, a sufficient quantity of normal samples is amassed to train a diffusion model capable of generating normal X-ray images. This pre-trained diffusion model is subsequently utilized to inpaint the head lesions present in the diseased X-rays, thereby preserving the tail classes as augmented training data. Additionally, we propose the integration of a Large Language Model Knowledge Guidance (LKG) module alongside a Progressive Incremental Learning (PIL) strategy to stabilize the inpainting fine-tuning process. Comprehensive evaluations conducted on the public lung datasets MIMIC and CheXpert demonstrate that the proposed method sets a new benchmark in performance.
format Preprint
id arxiv_https___arxiv_org_abs_2512_20980
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle X-ray Insights Unleashed: Pioneering the Enhancement of Multi-Label Long-Tail Data
Yang, Xinquan
Xie, Jinheng
Huang, Yawen
Li, Yuexiang
Huang, Huimin
Zheng, Hao
Wu, Xian
Zheng, Yefeng
Shen, Linlin
Computer Vision and Pattern Recognition
Long-tailed pulmonary anomalies in chest radiography present formidable diagnostic challenges. Despite the recent strides in diffusion-based methods for enhancing the representation of tailed lesions, the paucity of rare lesion exemplars curtails the generative capabilities of these approaches, thereby leaving the diagnostic precision less than optimal. In this paper, we propose a novel data synthesis pipeline designed to augment tail lesions utilizing a copious supply of conventional normal X-rays. Specifically, a sufficient quantity of normal samples is amassed to train a diffusion model capable of generating normal X-ray images. This pre-trained diffusion model is subsequently utilized to inpaint the head lesions present in the diseased X-rays, thereby preserving the tail classes as augmented training data. Additionally, we propose the integration of a Large Language Model Knowledge Guidance (LKG) module alongside a Progressive Incremental Learning (PIL) strategy to stabilize the inpainting fine-tuning process. Comprehensive evaluations conducted on the public lung datasets MIMIC and CheXpert demonstrate that the proposed method sets a new benchmark in performance.
title X-ray Insights Unleashed: Pioneering the Enhancement of Multi-Label Long-Tail Data
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2512.20980