Interpretable Link Prediction in AI-Driven Cancer Research: Uncovering Co-Authorship Patterns

Fuente: arXiv
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Autores principales: Mosallaie, Shahab, Schiffauerova, Andrea, Ebadi, Ashkan
Formato: Preprint
Publicado: 2025
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author Mosallaie, Shahab
Schiffauerova, Andrea
Ebadi, Ashkan
author_facet Mosallaie, Shahab
Schiffauerova, Andrea
Ebadi, Ashkan
contents Artificial intelligence (AI) is transforming cancer diagnosis and treatment. The intricate nature of this disease necessitates the collaboration of diverse stakeholders with varied expertise to ensure the effectiveness of cancer research. Despite its importance, forming effective interdisciplinary research teams remains challenging. Understanding and predicting collaboration patterns can help researchers, organizations, and policymakers optimize resources and foster impactful research. We examined co-authorship networks as a proxy for collaboration within AI-driven cancer research. Using 7,738 publications (2000-2017) from Scopus, we constructed 36 overlapping co-authorship networks representing new, persistent, and discontinued collaborations. We engineered both attribute-based and structure-based features and built four machine learning classifiers. Model interpretability was performed using Shapley Additive Explanations (SHAP). Random forest achieved the highest recall for all three types of examined collaborations. The discipline similarity score emerged as a crucial factor, positively affecting new and persistent patterns while negatively impacting discontinued collaborations. Additionally, high productivity and seniority were positively associated with discontinued links. Our findings can guide the formation of effective research teams, enhance interdisciplinary cooperation, and inform strategic policy decisions.
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institution arXiv
publishDate 2025
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spellingShingle Interpretable Link Prediction in AI-Driven Cancer Research: Uncovering Co-Authorship Patterns
Mosallaie, Shahab
Schiffauerova, Andrea
Ebadi, Ashkan
Digital Libraries
Artificial Intelligence
Artificial intelligence (AI) is transforming cancer diagnosis and treatment. The intricate nature of this disease necessitates the collaboration of diverse stakeholders with varied expertise to ensure the effectiveness of cancer research. Despite its importance, forming effective interdisciplinary research teams remains challenging. Understanding and predicting collaboration patterns can help researchers, organizations, and policymakers optimize resources and foster impactful research. We examined co-authorship networks as a proxy for collaboration within AI-driven cancer research. Using 7,738 publications (2000-2017) from Scopus, we constructed 36 overlapping co-authorship networks representing new, persistent, and discontinued collaborations. We engineered both attribute-based and structure-based features and built four machine learning classifiers. Model interpretability was performed using Shapley Additive Explanations (SHAP). Random forest achieved the highest recall for all three types of examined collaborations. The discipline similarity score emerged as a crucial factor, positively affecting new and persistent patterns while negatively impacting discontinued collaborations. Additionally, high productivity and seniority were positively associated with discontinued links. Our findings can guide the formation of effective research teams, enhance interdisciplinary cooperation, and inform strategic policy decisions.
title Interpretable Link Prediction in AI-Driven Cancer Research: Uncovering Co-Authorship Patterns
topic Digital Libraries
Artificial Intelligence
url https://arxiv.org/abs/2512.22181